Abstract
Growing evidence suggests that elevated cholesterol levels in mid-life are associated with increased risk of developing Alzheimer's disease (AD), and that statins might have a protective effect against AD and dementia. The Lipitor's Effect in Alzheimer's Dementia (LEADe) study tests the hypothesis that a statin (atorvastatin 80 mg daily) will provide a benefit on the course of mild to moderate AD in patients receiving background therapy of a cholinesterase inhibitor (donepezil 10 mg daily).
Original language | English |
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Pages (from-to) | 145-53 |
Number of pages | 9 |
Journal | Alzheimer's & Dementia: The Journal of the Alzheimer's Association |
Volume | 4 |
Issue number | 2 |
DOIs | |
Publication status | Published - Mar 2008 |
ASJC Scopus subject areas
- Epidemiology
- Geriatrics and Gerontology
- Health Policy
- Clinical Neurology
- Psychiatry and Mental health
- Cellular and Molecular Neuroscience
- Developmental Neuroscience