The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study

R Provenzano; A Besarab; I C Macdougall; D H Ellison; A P Maxwell; W Sulowicz; M Klinger; B Rutkowski; R Correa-Rotter; F C Dougherty; BA 16528 Study Investigators

The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study

R Provenzano, A Besarab, I C Macdougall, D H Ellison, A P Maxwell, W Sulowicz, M Klinger, B Rutkowski, R Correa-Rotter, F C Dougherty, BA 16528 Study Investigators

Research output: Contribution to journal › Article › peer-review

70 Citations (Scopus)

Abstract

This study was designed to assess the potential of the continuous erythropoietin receptor activator (C.E.R.A.) to correct anemia at extended administration intervals in erythropoiesis-stimulating agent-naīve patients with chronic kidney disease (CKD) not on dialysis and to determine its optimal starting dose.

Original language	English
Pages (from-to)	306-17
Number of pages	12
Journal	Clinical nephrology
Volume	67
Issue number	5
Publication status	Published - May 2007

Keywords

Adult
Aged
Aged, 80 and over
Analysis of Variance
Anemia
Area Under Curve
Biological Markers
Dose-Response Relationship, Drug
Erythropoiesis
Erythropoietin
Female
Ferritins
Follow-Up Studies
Hemoglobins
Humans
Kidney Failure, Chronic
Male
Middle Aged
Polyethylene Glycols
Recombinant Proteins
Regression Analysis
Renal Dialysis
Time Factors
Treatment Outcome

Cite this

Provenzano, R., Besarab, A., Macdougall, I. C., Ellison, D. H., Maxwell, A. P., Sulowicz, W., Klinger, M., Rutkowski, B., Correa-Rotter, R., Dougherty, F. C., & BA 16528 Study Investigators (2007). The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study. Clinical nephrology, 67(5), 306-17.

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title = "The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study",

abstract = "This study was designed to assess the potential of the continuous erythropoietin receptor activator (C.E.R.A.) to correct anemia at extended administration intervals in erythropoiesis-stimulating agent-naīve patients with chronic kidney disease (CKD) not on dialysis and to determine its optimal starting dose.",

keywords = "Adult, Aged, Aged, 80 and over, Analysis of Variance, Anemia, Area Under Curve, Biological Markers, Dose-Response Relationship, Drug, Erythropoiesis, Erythropoietin, Female, Ferritins, Follow-Up Studies, Hemoglobins, Humans, Kidney Failure, Chronic, Male, Middle Aged, Polyethylene Glycols, Recombinant Proteins, Regression Analysis, Renal Dialysis, Time Factors, Treatment Outcome",

author = "R Provenzano and A Besarab and Macdougall, {I C} and Ellison, {D H} and Maxwell, {A P} and W Sulowicz and M Klinger and B Rutkowski and R Correa-Rotter and Dougherty, {F C} and {BA 16528 Study Investigators}",

year = "2007",

month = may,

language = "English",

volume = "67",

pages = "306--17",

journal = "Clinical nephrology",

issn = "0301-0430",

publisher = "Dustri-Verlag Dr. Karl Feistle",

number = "5",

}

Provenzano, R, Besarab, A, Macdougall, IC, Ellison, DH, Maxwell, AP, Sulowicz, W, Klinger, M, Rutkowski, B, Correa-Rotter, R, Dougherty, FC & BA 16528 Study Investigators 2007, 'The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study', Clinical nephrology, vol. 67, no. 5, pp. 306-17.

The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study. / Provenzano, R; Besarab, A; Macdougall, I C et al.
In: Clinical nephrology, Vol. 67, No. 5, 05.2007, p. 306-17.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis

T2 - results of a phase II study

AU - Provenzano, R

AU - Besarab, A

AU - Macdougall, I C

AU - Ellison, D H

AU - Maxwell, A P

AU - Sulowicz, W

AU - Klinger, M

AU - Rutkowski, B

AU - Correa-Rotter, R

AU - Dougherty, F C

AU - BA 16528 Study Investigators

PY - 2007/5

Y1 - 2007/5

N2 - This study was designed to assess the potential of the continuous erythropoietin receptor activator (C.E.R.A.) to correct anemia at extended administration intervals in erythropoiesis-stimulating agent-naīve patients with chronic kidney disease (CKD) not on dialysis and to determine its optimal starting dose.

AB - This study was designed to assess the potential of the continuous erythropoietin receptor activator (C.E.R.A.) to correct anemia at extended administration intervals in erythropoiesis-stimulating agent-naīve patients with chronic kidney disease (CKD) not on dialysis and to determine its optimal starting dose.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Analysis of Variance

KW - Anemia

KW - Area Under Curve

KW - Biological Markers

KW - Dose-Response Relationship, Drug

KW - Erythropoiesis

KW - Erythropoietin

KW - Female

KW - Ferritins

KW - Follow-Up Studies

KW - Hemoglobins

KW - Humans

KW - Kidney Failure, Chronic

KW - Male

KW - Middle Aged

KW - Polyethylene Glycols

KW - Recombinant Proteins

KW - Regression Analysis

KW - Renal Dialysis

KW - Time Factors

KW - Treatment Outcome

M3 - Article

C2 - 17542340

SN - 0301-0430

VL - 67

SP - 306

EP - 317

JO - Clinical nephrology

JF - Clinical nephrology

IS - 5

ER -

The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study

Abstract

Keywords

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