The Effects of Anti-Hypertensive Drugs Evaluated Using Markov Modelling for Northern Ireland Chronic Kidney Disease Patients

A. Rainey, Karen Cairns, Adele Marshall, Michael Quinn, Gerard Savage, Damian Fogarty

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Abstract

The aim of this paper is to use Markov modelling to
investigate survival for particular types of kidney patients
in relation to their exposure to anti-hypertensive treatment
drugs. In order to monitor kidney function an intuitive three
point assessment is proposed through the collection of blood
samples in relation to Chronic Kidney Disease for Northern
Ireland patients. A five state Markov Model was devised
using specific transition probabilities for males and
females over all age groups. These transition probabilities
were then adjusted appropriately using relative risk scores
for the event death for different subgroups of patients. The
model was built using TreeAge software package in order to
explore the effects of anti-hypertensive drugs on patients.
Original languageEnglish
Pages530-535
Number of pages6
DOIs
Publication statusPublished - Jun 2008
Event21st IEEE International Symposium on Computer-Based Medical Systems (IEEE CBMS) - Jyvaskyla, Finland
Duration: 01 Jun 200801 Jun 2008

Conference

Conference21st IEEE International Symposium on Computer-Based Medical Systems (IEEE CBMS)
CountryFinland
CityJyvaskyla
Period01/06/200801/06/2008

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  • Cite this

    Rainey, A., Cairns, K., Marshall, A., Quinn, M., Savage, G., & Fogarty, D. (2008). The Effects of Anti-Hypertensive Drugs Evaluated Using Markov Modelling for Northern Ireland Chronic Kidney Disease Patients. 530-535. Paper presented at 21st IEEE International Symposium on Computer-Based Medical Systems (IEEE CBMS), Jyvaskyla, Finland. https://doi.org/10.1109/CBMS.2008.73