The impact of subthalamic deep brain stimulation on belief revision and social validation

Hannah Jergas*, Linnéa Grindegård, Thomas Schultze, Sharmili Edwin Thanarajah, Elke Kalbe, Thilo van Eimeren, Haidar S. Dafsari, Till A. Dembek, Veerle Visser-Vandewalle, Gereon R. Fink, Lars Timmermann, Leonhard Schilbach, Michael T. Barbe

*Corresponding author for this work

Research output: Contribution to journalLetterpeer-review

Abstract

We investigated whether Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) influences social validation as measured by a Judge-Advisor task. In contrast to healthy controls and patients with their DBS OFF, patients with their stimulation switched on do not experience a gain of confidence after receiving competent advice.

Original languageEnglish
Pages (from-to)84-86
Number of pages3
JournalParkinsonism and Related Disorders
Volume89
Early online date10 Jul 2021
DOIs
Publication statusPublished - Aug 2021
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported by the German Research Foundation [grant number 101434521].

Funding Information:
Till A. Dembek received speaker honoraria from Medtronic and Boston Scientific and grants from the Cologne Clinician Scientist Program (CCSP)/ Faculty of Medicine / University of Cologne . Funded by the German Research Foundation ( DFG , FI 773/15–1).

Funding Information:
Lars Timmermann received payments as a consultant for Boston Scientific , L.T. received honoraria as a speaker on symposia sponsored by UCB , Desitin, Boston Scientific , AbbVIE, Novartis , GlaxoSmithKline und DIAPLAN. The institution of L.T., not L.T. personally received funding by the German Research Foundation , the German Ministry of Education and Research and the Deutsche Parkinson Vereinigung ..

Funding Information:
Elke Kalbe received grants from the German Ministry of Education and Research , Parkinson Fonds Deutschland gGmbH, and the German Parkinson Society and honoraria from Oticon GmbH, Hamburg, Germany; Lilly Pharma GmbH, Bad Homburg, Germany; Bernafon AG, Bern, Switzerland; and Desitin GmbH, Hamburg, Germany.

Funding Information:
Thilo van Eimeren received consulting and lecture fees from Lundbeck A/S, Lilly Germany, and Shire Germany and research funding from the German Research Foundation (DFG), the Leibniz Association, and the EU-joint program for neurodegenerative disease research (JPND).Till A. Dembek received speaker honoraria from Medtronic and Boston Scientific and grants from the Cologne Clinician Scientist Program (CCSP)/Faculty of Medicine/University of Cologne. Funded by the German Research Foundation (DFG, FI 773/15?1).Lars Timmermann received payments as a consultant for Boston Scientific, L.T. received honoraria as a speaker on symposia sponsored by UCB, Desitin, Boston Scientific, AbbVIE, Novartis, GlaxoSmithKline und DIAPLAN. The institution of L.T., not L.T. personally received funding by the German Research Foundation, the German Ministry of Education and Research and the Deutsche Parkinson Vereinigung.Michael T. Barbe received speaker's honoraria from Medtronic, Boston Scientific, Abbott (formerly St. Jude), GE Medical, UCB, Apothekerverband K?ln e.V. and Bial as well as research funding from the Felgenhauer-Stiftung, Forschungspool Klinische Studien (University of Cologne), Horizon 2020 (Gondola), Medtronic (ODIS), and Boston Scientific and advisory honoraria for the IQWIG.This work was supported by the German Research Foundation [grant number 101434521].Elke Kalbe received grants from the German Ministry of Education and Research, Parkinson Fonds Deutschland gGmbH, and the German Parkinson Society and honoraria from Oticon GmbH, Hamburg, Germany; Lilly Pharma GmbH, Bad Homburg, Germany; Bernafon AG, Bern, Switzerland; and Desitin GmbH, Hamburg, Germany.

Funding Information:
Michael T. Barbe received speaker's honoraria from Medtronic, Boston Scientific, Abbott (formerly St. Jude), GE Medical, UCB , Apothekerverband Köln e.V. and Bial as well as research funding from the Felgenhauer-Stiftung, Forschungspool Klinische Studien ( University of Cologne ), Horizon 2020 (Gondola), Medtronic (ODIS), and Boston Scientific and advisory honoraria for the IQWIG.

Publisher Copyright:
© 2021 Elsevier Ltd

Keywords

  • Aged
  • Deep Brain Stimulation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Parkinson Disease/therapy
  • Self Concept
  • Social Behavior
  • Social Interaction
  • Subthalamic Nucleus

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

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