Abstract
Inflammatory bowel disease (IBD) is on the rise in the western world.1 The dynamic interplay between genetic susceptibility, the gut microbiome and host inflammatory reactions underlying IBD are still unclear. Shedding light onto these complex interactions in IBD, Chen et al.2 identified a key role for the negative immune regulator NLRP12 in shaping the composition of the gut microbiome and maintaining intestinal homeostasis.
Original language | English |
---|---|
Journal | Cellular and Molecular Immunology |
Early online date | 24 Jul 2017 |
DOIs | |
Publication status | Published - 24 Jul 2017 |
Fingerprint
Dive into the research topics of 'The innate immune receptor NLRP12 maintains intestinal homeostasis by regulating microbiome diversity'. Together they form a unique fingerprint.Student Theses
-
The role of inflammasomes in a murine model of acute respiratory distress syndrome (ARDS)
Author: Lau, J., Jul 2021Supervisor: Dombrowski, Y. (Supervisor), O'Kane, C. (Supervisor) & Fitzgerald, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy