The network structure of mania symptoms differs between people with and without binge eating

Helena L. Davies; Alicia J. Peel; Jessica Mundy; Dina Monssen; Saakshi Kakar; Molly R. Davies; Brett N. Adey; Chérie Armour; Gursharan Kalsi; Yuhao Lin; Ian Marsh; Henry C. Rogers; James T. R. Walters; Moritz Herle; Kiran Glen; Chelsea Mika Malouf; Emily J. Kelly; Thalia C. Eley; Janet Treasure; Gerome Breen; Christopher Hübel

doi:10.1111/bdi.13355

The network structure of mania symptoms differs between people with and without binge eating

Helena L. Davies, Alicia J. Peel, Jessica Mundy, Dina Monssen, Saakshi Kakar, Molly R. Davies, Brett N. Adey, Chérie Armour, Gursharan Kalsi, Yuhao Lin, Ian Marsh, Henry C. Rogers, James T. R. Walters, Moritz Herle, Kiran Glen, Chelsea Mika Malouf, Emily J. Kelly, Thalia C. Eley, Janet Treasure, Gerome BreenChristopher Hübel^*

^*Corresponding author for this work

School of Psychology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

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Abstract

Objectives
People with bipolar disorder who also report binge eating have increased psychopathology and greater impairment than those without binge eating. Whether this co-occurrence is related to binge eating as a symptom or presents differently across full-syndrome eating disorders with binge eating is unclear.

Methods
We first compared networks of 13 lifetime mania symptoms in 34,226 participants from the United Kingdom's National Institute for Health and Care Research BioResource with (n = 12,104) and without (n = 22,122) lifetime binge eating. Second, in the subsample with binge eating, we compared networks of mania symptoms in participants with lifetime anorexia nervosa binge-eating/purging (n = 825), bulimia nervosa (n = 3737), and binge-eating disorder (n = 3648).

Results
People with binge eating endorsed every mania symptom significantly more often than those without binge eating. Within the subsample, people with bulimia nervosa most often had the highest endorsement rate of each mania symptom. We found significant differences in network parameter statistics, including network structure (M = 0.25, p = 0.001) and global strength (S = 1.84, p = 0.002) when comparing the binge eating with no binge-eating participants. However, network structure differences were sensitive to reductions in sample size and the greater density of the latter network was explained by the large proportion of participants (34%) without mania symptoms. The structure of the anorexia nervosa binge-eating/purging network differed from the bulimia nervosa network (M = 0.66, p = 0.001), but the result was unstable.

Conclusions
Our results suggest that the presence and structure of mania symptoms may be more associated with binge eating as a symptom rather than any specific binge-type eating disorder. Further research with larger sample sizes is required to confirm our findings.

Original language	English
Pages (from-to)	592-607
Number of pages	16
Journal	Bipolar Disorders
Volume	25
Issue number	7
Early online date	12 Jun 2023
DOIs	https://doi.org/10.1111/bdi.13355
Publication status	Published - Nov 2023

Keywords

diagnosis
network analysis
binge‐eating disorder
bipolar disorder
bulimia nervosa
anorexia nervosa
signs and symptoms

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10.1111/bdi.13355Licence: CC BY

The network structure of mania symptoms differs between people with and without binge eating
Copyright 2023 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 3.13 MBLicence: CC BY

Cite this

Davies, H. L., Peel, A. J., Mundy, J., Monssen, D., Kakar, S., Davies, M. R., Adey, B. N., Armour, C., Kalsi, G., Lin, Y., Marsh, I., Rogers, H. C., Walters, J. T. R., Herle, M., Glen, K., Malouf, C. M., Kelly, E. J., Eley, T. C., Treasure, J., ... Hübel, C. (2023). The network structure of mania symptoms differs between people with and without binge eating. Bipolar Disorders, 25(7), 592-607. https://doi.org/10.1111/bdi.13355

@article{8ebb620bc7d94c699e97adc039ecc9da,

title = "The network structure of mania symptoms differs between people with and without binge eating",

abstract = "Objectives People with bipolar disorder who also report binge eating have increased psychopathology and greater impairment than those without binge eating. Whether this co-occurrence is related to binge eating as a symptom or presents differently across full-syndrome eating disorders with binge eating is unclear. Methods We first compared networks of 13 lifetime mania symptoms in 34,226 participants from the United Kingdom's National Institute for Health and Care Research BioResource with (n = 12,104) and without (n = 22,122) lifetime binge eating. Second, in the subsample with binge eating, we compared networks of mania symptoms in participants with lifetime anorexia nervosa binge-eating/purging (n = 825), bulimia nervosa (n = 3737), and binge-eating disorder (n = 3648). Results People with binge eating endorsed every mania symptom significantly more often than those without binge eating. Within the subsample, people with bulimia nervosa most often had the highest endorsement rate of each mania symptom. We found significant differences in network parameter statistics, including network structure (M = 0.25, p = 0.001) and global strength (S = 1.84, p = 0.002) when comparing the binge eating with no binge-eating participants. However, network structure differences were sensitive to reductions in sample size and the greater density of the latter network was explained by the large proportion of participants (34\%) without mania symptoms. The structure of the anorexia nervosa binge-eating/purging network differed from the bulimia nervosa network (M = 0.66, p = 0.001), but the result was unstable. Conclusions Our results suggest that the presence and structure of mania symptoms may be more associated with binge eating as a symptom rather than any specific binge-type eating disorder. Further research with larger sample sizes is required to confirm our findings.",

keywords = "diagnosis, network analysis, binge‐eating disorder, bipolar disorder, bulimia nervosa, anorexia nervosa, signs and symptoms",

author = "Davies, \{Helena L.\} and Peel, \{Alicia J.\} and Jessica Mundy and Dina Monssen and Saakshi Kakar and Davies, \{Molly R.\} and Adey, \{Brett N.\} and Ch{\'e}rie Armour and Gursharan Kalsi and Yuhao Lin and Ian Marsh and Rogers, \{Henry C.\} and Walters, \{James T. R.\} and Moritz Herle and Kiran Glen and Malouf, \{Chelsea Mika\} and Kelly, \{Emily J.\} and Eley, \{Thalia C.\} and Janet Treasure and Gerome Breen and Christopher H{\"u}bel",

year = "2023",

month = nov,

doi = "10.1111/bdi.13355",

language = "English",

volume = "25",

pages = "592--607",

journal = "Bipolar Disorders",

issn = "1398-5647",

publisher = "Blackwell Munksgaard",

number = "7",

}

Davies, HL, Peel, AJ, Mundy, J, Monssen, D, Kakar, S, Davies, MR, Adey, BN, Armour, C, Kalsi, G, Lin, Y, Marsh, I, Rogers, HC, Walters, JTR, Herle, M, Glen, K, Malouf, CM, Kelly, EJ, Eley, TC, Treasure, J, Breen, G & Hübel, C 2023, 'The network structure of mania symptoms differs between people with and without binge eating', Bipolar Disorders, vol. 25, no. 7, pp. 592-607. https://doi.org/10.1111/bdi.13355

TY - JOUR

T1 - The network structure of mania symptoms differs between people with and without binge eating

AU - Davies, Helena L.

AU - Peel, Alicia J.

AU - Mundy, Jessica

AU - Monssen, Dina

AU - Kakar, Saakshi

AU - Davies, Molly R.

AU - Adey, Brett N.

AU - Armour, Chérie

AU - Kalsi, Gursharan

AU - Lin, Yuhao

AU - Marsh, Ian

AU - Rogers, Henry C.

AU - Walters, James T. R.

AU - Herle, Moritz

AU - Glen, Kiran

AU - Malouf, Chelsea Mika

AU - Kelly, Emily J.

AU - Eley, Thalia C.

AU - Treasure, Janet

AU - Breen, Gerome

AU - Hübel, Christopher

PY - 2023/11

Y1 - 2023/11

N2 - Objectives People with bipolar disorder who also report binge eating have increased psychopathology and greater impairment than those without binge eating. Whether this co-occurrence is related to binge eating as a symptom or presents differently across full-syndrome eating disorders with binge eating is unclear. Methods We first compared networks of 13 lifetime mania symptoms in 34,226 participants from the United Kingdom's National Institute for Health and Care Research BioResource with (n = 12,104) and without (n = 22,122) lifetime binge eating. Second, in the subsample with binge eating, we compared networks of mania symptoms in participants with lifetime anorexia nervosa binge-eating/purging (n = 825), bulimia nervosa (n = 3737), and binge-eating disorder (n = 3648). Results People with binge eating endorsed every mania symptom significantly more often than those without binge eating. Within the subsample, people with bulimia nervosa most often had the highest endorsement rate of each mania symptom. We found significant differences in network parameter statistics, including network structure (M = 0.25, p = 0.001) and global strength (S = 1.84, p = 0.002) when comparing the binge eating with no binge-eating participants. However, network structure differences were sensitive to reductions in sample size and the greater density of the latter network was explained by the large proportion of participants (34%) without mania symptoms. The structure of the anorexia nervosa binge-eating/purging network differed from the bulimia nervosa network (M = 0.66, p = 0.001), but the result was unstable. Conclusions Our results suggest that the presence and structure of mania symptoms may be more associated with binge eating as a symptom rather than any specific binge-type eating disorder. Further research with larger sample sizes is required to confirm our findings.

AB - Objectives People with bipolar disorder who also report binge eating have increased psychopathology and greater impairment than those without binge eating. Whether this co-occurrence is related to binge eating as a symptom or presents differently across full-syndrome eating disorders with binge eating is unclear. Methods We first compared networks of 13 lifetime mania symptoms in 34,226 participants from the United Kingdom's National Institute for Health and Care Research BioResource with (n = 12,104) and without (n = 22,122) lifetime binge eating. Second, in the subsample with binge eating, we compared networks of mania symptoms in participants with lifetime anorexia nervosa binge-eating/purging (n = 825), bulimia nervosa (n = 3737), and binge-eating disorder (n = 3648). Results People with binge eating endorsed every mania symptom significantly more often than those without binge eating. Within the subsample, people with bulimia nervosa most often had the highest endorsement rate of each mania symptom. We found significant differences in network parameter statistics, including network structure (M = 0.25, p = 0.001) and global strength (S = 1.84, p = 0.002) when comparing the binge eating with no binge-eating participants. However, network structure differences were sensitive to reductions in sample size and the greater density of the latter network was explained by the large proportion of participants (34%) without mania symptoms. The structure of the anorexia nervosa binge-eating/purging network differed from the bulimia nervosa network (M = 0.66, p = 0.001), but the result was unstable. Conclusions Our results suggest that the presence and structure of mania symptoms may be more associated with binge eating as a symptom rather than any specific binge-type eating disorder. Further research with larger sample sizes is required to confirm our findings.

KW - diagnosis

KW - network analysis

KW - binge‐eating disorder

KW - bipolar disorder

KW - bulimia nervosa

KW - anorexia nervosa

KW - signs and symptoms

U2 - 10.1111/bdi.13355

DO - 10.1111/bdi.13355

M3 - Article

SN - 1398-5647

VL - 25

SP - 592

EP - 607

JO - Bipolar Disorders

JF - Bipolar Disorders

IS - 7

ER -

The network structure of mania symptoms differs between people with and without binge eating

Abstract

Keywords

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