The place of sperm DNA fragmentation testing in current day fertility management

Research output: Contribution to journalLiterature review

13 Citations (Scopus)
409 Downloads (Pure)

Abstract

In this debate article, I am going to set out the case that sperm DNA fragmentation testing is essential in current day fertility management because-
• Our current semen analysis testing is unfit for purpose
• Sperm DNA damage testing has strong associations with every fertility check
point
• Sperm DNA damage testing has strong associations with miscarriage
• Sperm DNA testing can explain ‘unexplained’ infertility
• There are reasons why sperm with poor DNA are successful in ICSI
• There are no non-invasive sperm function tests that provide the same
information
• We need to take a fresh look at the ‘evidence’ against sperm DNA testing
• We have no reason to wait. There are benefits for clinics and couples alike.

Original languageEnglish
Pages (from-to)78-82
JournalMiddle East Fertility Society Journal
Volume18
Issue number2
Early online date08 Mar 2013
DOIs
Publication statusPublished - Jun 2013

Fingerprint

DNA Fragmentation
Fertility
Spermatozoa
DNA Damage
DNA
Semen Analysis
Intracytoplasmic Sperm Injections
Spontaneous Abortion
Infertility

Keywords

  • sperm DNA fertility testing

Cite this

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The place of sperm DNA fragmentation testing in current day fertility management. / Lewis, Sheena E.M.

In: Middle East Fertility Society Journal, Vol. 18, No. 2, 06.2013, p. 78-82.

Research output: Contribution to journalLiterature review

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AB - In this debate article, I am going to set out the case that sperm DNA fragmentation testing is essential in current day fertility management because-• Our current semen analysis testing is unfit for purpose• Sperm DNA damage testing has strong associations with every fertility check point• Sperm DNA damage testing has strong associations with miscarriage• Sperm DNA testing can explain ‘unexplained’ infertility• There are reasons why sperm with poor DNA are successful in ICSI• There are no non-invasive sperm function tests that provide the same information• We need to take a fresh look at the ‘evidence’ against sperm DNA testing• We have no reason to wait. There are benefits for clinics and couples alike.

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