The place of sperm DNA fragmentation testing in current day fertility management

Sheena E.M. Lewis

doi:10.1016/j.mefs.2013.01.010

The place of sperm DNA fragmentation testing in current day fertility management

Sheena E.M. Lewis

Research output: Contribution to journal › Literature review › peer-review

17 Citations (Scopus)

830 Downloads (Pure)

Abstract

In this debate article, I am going to set out the case that sperm DNA fragmentation testing is essential in current day fertility management because-
• Our current semen analysis testing is unfit for purpose
• Sperm DNA damage testing has strong associations with every fertility check
point
• Sperm DNA damage testing has strong associations with miscarriage
• Sperm DNA testing can explain ‘unexplained’ infertility
• There are reasons why sperm with poor DNA are successful in ICSI
• There are no non-invasive sperm function tests that provide the same
information
• We need to take a fresh look at the ‘evidence’ against sperm DNA testing
• We have no reason to wait. There are benefits for clinics and couples alike.

Original language	English
Pages (from-to)	78-82
Journal	Middle East Fertility Society Journal
Volume	18
Issue number	2
Early online date	08 Mar 2013
DOIs	https://doi.org/10.1016/j.mefs.2013.01.010
Publication status	Published - Jun 2013

Keywords

sperm DNA fertility testing

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10.1016/j.mefs.2013.01.010Licence: CC BY-NC-ND

The place of sperm DNA fragmentation testing in current day fertility management
Copyright 2013 Production and hosting by Elsevier B.V. on behalf of Middle East Fertility Society. This is an open access article published under a Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/3.0/), which permits distribution and reproduction for non-commercial purposes, provided the author and source are cited.
Final published version, 313 KBLicence: CC BY-NC-ND

Cite this

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AB - In this debate article, I am going to set out the case that sperm DNA fragmentation testing is essential in current day fertility management because-• Our current semen analysis testing is unfit for purpose• Sperm DNA damage testing has strong associations with every fertility check point• Sperm DNA damage testing has strong associations with miscarriage• Sperm DNA testing can explain ‘unexplained’ infertility• There are reasons why sperm with poor DNA are successful in ICSI• There are no non-invasive sperm function tests that provide the same information• We need to take a fresh look at the ‘evidence’ against sperm DNA testing• We have no reason to wait. There are benefits for clinics and couples alike.

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The place of sperm DNA fragmentation testing in current day fertility management

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Keywords

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