The role of higher-order chromatin structure in the yield and distribution of DNA double-strand breaks in cells irradiated with X-rays or alpha-particles

H.C. Newman, Kevin Prise, B.D. Michael

Research output: Contribution to journalArticle

Abstract

Purpose: To determine whether the non-random distributions of DNA double-strand breaks in cells observed after alpha-particle irradiation are related to the higher-order structure of the chromatin within the nucleus.
Original languageEnglish
Pages (from-to)1085-1093
Number of pages9
JournalInternational journal of radiation biology
Volume76
Publication statusPublished - 2000

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