The role of microscopy in the investigation of paramyosin as a vaccine candidate against Schistosoma japonicum

Geoffry N. Gobert*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

There has been growing interest in paramyosin as a vaccine component to combat schistosomiasis. Immunological and molecular techniques have been used in the past to investigate the effectiveness of a paramyosin vaccine as an anti-schistosomal treatment. However, recent localization studies at ultrastructual and morphological levels have highlighted a number of questions concerning the role of paramyosin within schistosome parasites. Debates about how a non-surface protein such a paramyosin might provide protection against schistosome infections have recently been addressed by microscopy results. Immunolocalization studies have indicated multiple functions of paramyosin within the parasite and provided insights into how a vaccine may target the parasite, as discussed here by Geoffrey Gobert.

Original languageEnglish
Pages (from-to)115-118
Number of pages4
JournalParasitology Today
Volume14
Issue number3
DOIs
Publication statusPublished - 01 Jan 1998
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology

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