The study of the interactions between naproxen and N-acetyl-L-tyrosine ethyl ester

Rebecca Craig, Dorota Sobczuk, Marta Nogueroles, Slavica Radisic, Boheng Shen, Susanne Simon

Research output: Contribution to journalArticle

Abstract

The interaction between naproxen and N-acetyl-L-tyrosine ethyl ester was investigated using UV-Vis absorption and fluorescence methods and the results indicate that an interaction is present in the ground state. Hydrogen bond formation between these two molecules in complexation was illustrated by the computer optimised complex. This theory was supported by the increased fluorescence lifetime decay observed, the Gibbs free energy for complexation and also by the geometry of the complex.
Original languageEnglish
Pages (from-to)23-36
JournalZeszyty Naukowe. Chemia Spozywcza i Biotechnologia
Publication statusPublished - 2006

Keywords

  • Analysis
  • Fluorescence spectroscopy

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