The synthesis of BRL 49653 - a novel and potent antihyperglycemic agent.

B.C.C. Cantello, M.A. Cawthorne, David Haigh, R.M. Hindley, S.A. Smith, P. Thurlby

Research output: Contribution to journalArticle

Abstract

Modifications based upon a metabolite of ciglitazone afforded BRL 49653 (I), a novel potent insulin sensitizer. A facile synthesis of this compd. is described.
Original languageEnglish
Pages (from-to)1181-1184
Number of pages4
JournalBioorganic & Medicinal Chemistry Letters
Volume4
Publication statusPublished - 1994

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    Cantello, B. C. C., Cawthorne, M. A., Haigh, D., Hindley, R. M., Smith, S. A., & Thurlby, P. (1994). The synthesis of BRL 49653 - a novel and potent antihyperglycemic agent. Bioorganic & Medicinal Chemistry Letters, 4, 1181-1184.