The micro-irradiation technique continues to be highly relevant to a number of radiobiological studies in vitro. In particular, studies of the bystander effect show that direct damage to cells is not the only trigger for radiation-induced effects, but that unirradiated cells can also respond to signals from irradiated neighbours. Furthermore, the bystander response can be initiated even when no energy is deposited in the genomic DNA of the irradiated cell (i.e. by targeting just the cytoplasm).
|Number of pages||4|
|Journal||Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine|
|Publication status||Published - Mar 2009|
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