TY - JOUR
T1 - The use of microbeams to investigate radiation damage in living cells.
AU - Folkard, M.
AU - Prise, Kevin
AU - Grime, G.
AU - Kirkby, K.
AU - Vojnovic, B.
PY - 2009/3
Y1 - 2009/3
N2 - The micro-irradiation technique continues to be highly relevant to a number of radiobiological studies in vitro. In particular, studies of the bystander effect show that direct damage to cells is not the only trigger for radiation-induced effects, but that unirradiated cells can also respond to signals from irradiated neighbours. Furthermore, the bystander response can be initiated even when no energy is deposited in the genomic DNA of the irradiated cell (i.e. by targeting just the cytoplasm).
AB - The micro-irradiation technique continues to be highly relevant to a number of radiobiological studies in vitro. In particular, studies of the bystander effect show that direct damage to cells is not the only trigger for radiation-induced effects, but that unirradiated cells can also respond to signals from irradiated neighbours. Furthermore, the bystander response can be initiated even when no energy is deposited in the genomic DNA of the irradiated cell (i.e. by targeting just the cytoplasm).
UR - http://www.scopus.com/inward/record.url?scp=58549100663&partnerID=8YFLogxK
U2 - 10.1016/j.apradiso.2008.06.015
DO - 10.1016/j.apradiso.2008.06.015
M3 - Article
C2 - 18710814
VL - 67(3)
SP - 436
EP - 439
JO - Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
JF - Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
IS - 3
ER -