The utilization of 4-aminobutylphosphonate as sole nitrogen source by a strain of Kluyveromyces fragilis

Nigel G. Ternan*, Geoffrey McMullan

*Corresponding author for this work

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A strain of the yeast Kluyveromyces fragilis was screened for its ability to utilize a range of synthetic and natural organophosphonate compounds as the sole source of phosphorus, nitrogen or carbon. Only 4-aminobutylphosphonate was utilized as sole nitrogen source with protein yields increasing proportionally with substrate concentrations up to 10 mM. No 4-aminobutylphosphonate metabolizing enzyme activity was detectable in cell-free extracts prepared from K. fragilis pregrown on 2.5 mM 4-aminobutylphosphonate. None of the organophosphonates tested served as a source of carbon or phosphorus for K. fragilis. Copyright (C) 2000 Federation of European Microbiological Societies.

Original languageEnglish
Pages (from-to)237-240
Number of pages4
JournalFEMS Microbiology Letters
Volume184
Issue number2
DOIs
Publication statusPublished - 15 Mar 2000
Externally publishedYes

Keywords

  • Biodegradation
  • Organophosphonate
  • pho regulon
  • Yeast

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Microbiology

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