Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours

Manuel Salto-Tellez, M.E. Nga, H.C. Han, A.S.C. Wong, C.K. Lee, D. Anuar, S.S. Ng, M. Ho, A. Wee, Y.H. Chan, R. Soong

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

A tissue microarray analysis of 22 proteins in gastrointestinal stromal tumours ( GIST), followed by an unsupervised, hierarchical monothetic cluster statistical analysis of the results, allowed us to detect a vascular endothelial growth factor ( VEGF) protein overexpression signature discriminator of prognosis in GIST, and discover novel VEGF-A DNA variants that may have functional significance.
Original languageEnglish
Pages (from-to)776-782
Number of pages7
JournalBritish Journal of Cancer
Volume96
Issue number5
DOIs
Publication statusPublished - 12 Mar 2007

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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