Total Synthesis of Bryostatin 1: A Short Route

Karl J Hale, Soraya Manaviazar

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


A chemical legacy: Keck and his team have chemically pursued the bryostatin 1 structure with great vigor in recent years and, in late 2010, they finally completed their quest of developing a short and efficient total synthesis of this complex natural product (see structure). The present Highlight provides a brief but nevertheless detailed overview of the Keck synthesis and its chemical legacy in terms of new reactions.
Original languageEnglish
Pages (from-to)8786-8789
Number of pages4
JournalAngewandte Chemie International Edition
Issue number38
Publication statusPublished - 12 Sep 2011

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis


Dive into the research topics of 'Total Synthesis of Bryostatin 1: A Short Route'. Together they form a unique fingerprint.

Cite this