Total Synthesis of Bryostatin 1: A Short Route

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29 Citations (Scopus)

Abstract

A chemical legacy: Keck and his team have chemically pursued the bryostatin 1 structure with great vigor in recent years and, in late 2010, they finally completed their quest of developing a short and efficient total synthesis of this complex natural product (see structure). The present Highlight provides a brief but nevertheless detailed overview of the Keck synthesis and its chemical legacy in terms of new reactions.
Original languageEnglish
Pages (from-to)8786-8789
Number of pages4
JournalAngewandte Chemie International Edition
Volume2011
Issue number38
DOIs
Publication statusPublished - 12 Sep 2011

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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