TY - GEN
T1 - Towards non-invasive deep brain stimulation using temporal interference method
AU - Gholami, Mehdi
AU - Ghobadzadeh, Farshid
AU - Yazdanshenas, Fatemeh
AU - Yazdani, Amir
AU - Neshat, Mohammad
PY - 2021/10/4
Y1 - 2021/10/4
N2 - In this paper, we examine the effectiveness of the temporal interference method through simulations and experiments on phantom models. In this method, the electrodes are placed on the scalp, and no physical damage is done to the subject. In contrast to other non-invasive stimulation methods in which a large part of the brain might be under the influence of the stimulation, the TI method not only has the ability to focus the stimulation at a specific point (with a certain resolution), but also it can move the stimulated spot. In the simulations, we study the current interference pattern inside the human head model, and we use the Hodgkin-Huxley model to map action potentials in our simulations. Moreover, we study the effect of different parameters on how to move the stimulation spot. Our simulation results are verified against experimental measurements on a phantom.
AB - In this paper, we examine the effectiveness of the temporal interference method through simulations and experiments on phantom models. In this method, the electrodes are placed on the scalp, and no physical damage is done to the subject. In contrast to other non-invasive stimulation methods in which a large part of the brain might be under the influence of the stimulation, the TI method not only has the ability to focus the stimulation at a specific point (with a certain resolution), but also it can move the stimulated spot. In the simulations, we study the current interference pattern inside the human head model, and we use the Hodgkin-Huxley model to map action potentials in our simulations. Moreover, we study the effect of different parameters on how to move the stimulation spot. Our simulation results are verified against experimental measurements on a phantom.
KW - Deep brain stimulation (DBS)
KW - Modulation depth
KW - Spatial resolution
KW - Temporal interference (TI)
U2 - 10.1109/ICEE52715.2021.9544154
DO - 10.1109/ICEE52715.2021.9544154
M3 - Conference contribution
AN - SCOPUS:85117478127
SN - 9781665433662
T3 - ICEE Proceedings
SP - 950
EP - 954
BT - Proceedings of the 29th Iranian Conference on Electrical Engineering, ICEE 2021
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 29th Iranian Conference on Electrical Engineering 2021
Y2 - 18 May 2021 through 20 May 2021
ER -