Towards Organic Electronic Materials for Electrically Stimulated Gene Delivery

John G. Hardy; Christine E. Schmidt

doi:10.4155/9781910420430

Towards Organic Electronic Materials for Electrically Stimulated Gene Delivery

John G. Hardy, Christine E. Schmidt

School of Pharmacy

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The cell-specific delivery of polynucleic acids (e.g., DNA, RNA), gene therapy, has the potential to treat various diseases. In this chapter we discuss the use of organic electronic materials as non-viral gene delivery vectors and the great potential for electrochemically triggered gene delivery. We highlight some examples in this chapter based on fullerenes (bucky balls and carbon nanotubes), graphenes and electroactive polymers, particularly those that include experiments in vivo.

Original language	English
Title of host publication	Nanoparticles for biotherapeutic therapy
Editors	Joshua Ramsey, M Laird Forrest
Publisher	Future Science Group
Pages	58-70
Number of pages	13
Volume	2
ISBN (Electronic)	9781910420430
DOIs	https://doi.org/10.4155/9781910420430 https://doi.org/10.4155/fseb2013.14.9
Publication status	Published - Jul 2015

Keywords

gene delivery
organic electronics
CONJUGATED POLYMERS
graphene
CARBON NANOTUBE
fullerene
bucky balls
conducting polymers

ASJC Scopus subject areas

General Chemistry
Biomedical Engineering
Medicine (miscellaneous)
General Biochemistry,Genetics and Molecular Biology

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http://www.futuremedicine.com/doi/book/10.4155/9781910420430

Cite this

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abstract = "The cell-specific delivery of polynucleic acids (e.g., DNA, RNA), gene therapy, has the potential to treat various diseases. In this chapter we discuss the use of organic electronic materials as non-viral gene delivery vectors and the great potential for electrochemically triggered gene delivery. We highlight some examples in this chapter based on fullerenes (bucky balls and carbon nanotubes), graphenes and electroactive polymers, particularly those that include experiments in vivo.",

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KW - gene delivery

KW - organic electronics

KW - CONJUGATED POLYMERS

KW - graphene

KW - CARBON NANOTUBE

KW - fullerene

KW - bucky balls

KW - conducting polymers

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M3 - Chapter

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A2 - Forrest, M Laird

PB - Future Science Group

ER -

Towards Organic Electronic Materials for Electrically Stimulated Gene Delivery

Abstract

Keywords

ASJC Scopus subject areas

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