Towards Organic Electronic Materials for Electrically Stimulated Gene Delivery

John G. Hardy, Christine E. Schmidt

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The cell-specific delivery of polynucleic acids (e.g., DNA, RNA), gene therapy, has the potential to treat various diseases. In this chapter we discuss the use of organic electronic materials as non-viral gene delivery vectors and the great potential for electrochemically triggered gene delivery. We highlight some examples in this chapter based on fullerenes (bucky balls and carbon nanotubes), graphenes and electroactive polymers, particularly those that include experiments in vivo.
Original languageEnglish
Title of host publicationNanoparticles for biotherapeutic therapy
EditorsJoshua Ramsey, M Laird Forrest
PublisherFuture Science Group
Pages58-70
Number of pages13
Volume2
ISBN (Electronic)9781910420430
DOIs
Publication statusPublished - Jul 2015

Keywords

  • gene delivery
  • organic electronics
  • CONJUGATED POLYMERS
  • graphene
  • CARBON NANOTUBE
  • fullerene
  • bucky balls
  • conducting polymers

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Medicine (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)

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