TY - JOUR
T1 - Trends in the epidemiology of Candida bloodstream infections in Northern Ireland between January 1984 and December 2000
AU - McMullan, R.
AU - McClurg, R.
AU - Xu, J.
AU - Moore, J.E.
AU - Millar, B.C.
AU - Crowe, M.
AU - Hedderwick, S.
N1 - MEDLINE® is the source for the MeSH terms of this document.
PY - 2002/7/1
Y1 - 2002/7/1
N2 - Objective: To describe the epidemiology of Candida bloodstream infections (BSI) in Northern Ireland. Methods: Retrospective collation of data relating to all clinically significant BSI in a university teaching hospital, which had been recorded prospectively, between 1984 and 2000. Results: One hundred and forty five episodes of candidaemia occurred in 144 patients (of mean age 56.6 years). The contribution of Candida spp. towards all significant BSI increased from 2.00% to 2.5%. C. albicans was the most frequently isolated species, however, its incidence fell from 70% to 53% during the study period. The greatest increase in incidence was seen with C. glabrata which was the most common non-albicans species. Twenty-nine per cent of isolates occurred in patients from an intensive care unit and, surprisingly, a further 25.5% occurred in patients from a surgical service. Conclusion: There appears to be several subtle differences in the epidemiology of candidal BSI between Northern Ireland and other countries.
AB - Objective: To describe the epidemiology of Candida bloodstream infections (BSI) in Northern Ireland. Methods: Retrospective collation of data relating to all clinically significant BSI in a university teaching hospital, which had been recorded prospectively, between 1984 and 2000. Results: One hundred and forty five episodes of candidaemia occurred in 144 patients (of mean age 56.6 years). The contribution of Candida spp. towards all significant BSI increased from 2.00% to 2.5%. C. albicans was the most frequently isolated species, however, its incidence fell from 70% to 53% during the study period. The greatest increase in incidence was seen with C. glabrata which was the most common non-albicans species. Twenty-nine per cent of isolates occurred in patients from an intensive care unit and, surprisingly, a further 25.5% occurred in patients from a surgical service. Conclusion: There appears to be several subtle differences in the epidemiology of candidal BSI between Northern Ireland and other countries.
UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-0036665270&md5=8c36050b6ce7815a6d7017c1103c7fe9
U2 - 10.1053/jinf.2002.0999
DO - 10.1053/jinf.2002.0999
M3 - Article
AN - SCOPUS:0036665270
SN - 0163-4453
VL - 45
SP - 25
EP - 28
JO - Journal of Infection
JF - Journal of Infection
IS - 1
ER -