Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin. Evidence that IRS-1 phosphorylation is not sufficient for normal insulin action.

Research output: Contribution to journalArticle

47 Citations (Scopus)
Original languageEnglish
Pages (from-to)7134-7140
Number of pages7
JournalJournal of Biological Chemistry
Volume271(12)
Publication statusPublished - 1996

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