Value of SPECT imaging in patients with TTR-amyloid: ratios are not enough

Muzna Hussain; Patrick Collier; Wael Jaber

doi:10.1007/s12350-019-01997-1

Value of SPECT imaging in patients with TTR-amyloid: ratios are not enough

Muzna Hussain, Patrick Collier, Wael Jaber

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

99m-technetium pyrophosphate (Tc-PyP) single-photon emission computed tomography (SPECT) is increasingly used to diagnose cardiac amyloidosis (CA) 1. A heart-to-contralateral (H/CL) ratio of >1.5 has been reported to be specific and sensitive in diagnosing transthyretin (TTR) CA2. We present two cases in which SPECT imaging revealed a low H/CL in the setting of a prior infarct.

Original language	English
Pages (from-to)	747-749
Number of pages	3
Journal	Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Volume	28
Issue number	2
Early online date	19 Dec 2019
DOIs	https://doi.org/10.1007/s12350-019-01997-1
Publication status	Published - Apr 2021
Externally published	Yes

Keywords

Aged
Amyloid Neuropathies, Familial/diagnostic imaging
Cardiomyopathies/diagnostic imaging
Humans
Male
Radiopharmaceuticals
Technetium Tc 99m Pyrophosphate
Tomography, Emission-Computed, Single-Photon/methods

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10.1007/s12350-019-01997-1Licence: Unspecified

Cardiovascular disease in patients with cancer or amyloidosis
Hussain, M. (Author), Collier, P. (Supervisor), Watson, C. (Supervisor) & Grieve, D. (Supervisor), Jul 2023
Student thesis: Doctoral Thesis › Doctor of Philosophy

Cite this

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title = "Value of SPECT imaging in patients with TTR-amyloid: ratios are not enough",

abstract = "99m-technetium pyrophosphate (Tc-PyP) single-photon emission computed tomography (SPECT) is increasingly used to diagnose cardiac amyloidosis (CA) 1. A heart-to-contralateral (H/CL) ratio of >1.5 has been reported to be specific and sensitive in diagnosing transthyretin (TTR) CA2. We present two cases in which SPECT imaging revealed a low H/CL in the setting of a prior infarct.",

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author = "Muzna Hussain and Patrick Collier and Wael Jaber",

year = "2021",

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doi = "10.1007/s12350-019-01997-1",

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AU - Hussain, Muzna

AU - Collier, Patrick

AU - Jaber, Wael

PY - 2021/4

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N2 - 99m-technetium pyrophosphate (Tc-PyP) single-photon emission computed tomography (SPECT) is increasingly used to diagnose cardiac amyloidosis (CA) 1. A heart-to-contralateral (H/CL) ratio of >1.5 has been reported to be specific and sensitive in diagnosing transthyretin (TTR) CA2. We present two cases in which SPECT imaging revealed a low H/CL in the setting of a prior infarct.

AB - 99m-technetium pyrophosphate (Tc-PyP) single-photon emission computed tomography (SPECT) is increasingly used to diagnose cardiac amyloidosis (CA) 1. A heart-to-contralateral (H/CL) ratio of >1.5 has been reported to be specific and sensitive in diagnosing transthyretin (TTR) CA2. We present two cases in which SPECT imaging revealed a low H/CL in the setting of a prior infarct.

KW - Aged

KW - Amyloid Neuropathies, Familial/diagnostic imaging

KW - Cardiomyopathies/diagnostic imaging

KW - Humans

KW - Male

KW - Radiopharmaceuticals

KW - Technetium Tc 99m Pyrophosphate

KW - Tomography, Emission-Computed, Single-Photon/methods

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DO - 10.1007/s12350-019-01997-1

M3 - Article

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SN - 1071-3581

VL - 28

SP - 747

EP - 749

JO - Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

JF - Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

IS - 2

ER -

Value of SPECT imaging in patients with TTR-amyloid: ratios are not enough

Abstract

Keywords

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Student theses

Cardiovascular disease in patients with cancer or amyloidosis

Cite this