Vitreomacular interface alterations following peripheral laser retinopexy: Interface changes after laser

Gian Marco Tosi*, Tommaso Bacci, Antonio Tarantello, Davide Marigliani, Giacomo Calmanti, Maria Sole Polito, Giovanni Neri, Fiorella Fusco, Gabriele Cevenini, Gianni Virgili

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To demonstrate the morphological outcomes of macular hole following prophylactic peripheral laser retinopexy (PPLR). Methods: Our retrospective case-control analysis included 92 eyes, 55 in the laser group and 37 in the non-laser group. Fifty-five patients were subjected to prophylactic peripheral laser retinopexy in preparation for pars plana vitrectomy for macular hole, with and without vitreomacular adhesion (laser group). Before and after prophylactic peripheral laser retinopexy, we evaluated any changes in vitreomacular anatomy by optical coherence tomography. Optical coherence tomography changes were also analyzed in the visits preceding pars plana vitrectomy in 37 macular hole eyes not subjected to prophylactic peripheral laser retinopexy (non-laser group). Results: In the laser group, 7 out of 55 eyes (12.7%) showed macular hole closure (6 out of 18 macular hole eyes with vitreomacular adhesion (33.3%) and 1 out of 37 eyes without vitreomacular adhesion (2.7%)), while no patients showed macular hole closure in the non-laser group (p < 0.05). The mean width of the seven closed macular hole was 191.4 µm (range: 59–282 µm). In all except one of the six macular hole eyes with vitreomacular adhesion, the macular hole closed without vitreomacular adhesion release. In our analysis of the patient subgroup with vitreomacular adhesion, we observed a release of vitreomacular adhesion in 3 out of 18 eyes (16.6%) in the laser group and in 1 out of 13 eyes (7.6%) in the non-laser group (p > 0.05). Conclusion: These findings support a possible beneficial role for prophylactic peripheral laser retinopexy in selected individuals with macular hole.

Original languageEnglish
Pages (from-to)941-947
Number of pages7
JournalEuropean Journal of Ophthalmology
Volume30
Issue number5
Early online date20 Sep 2019
DOIs
Publication statusPublished - 01 Sep 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2019.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Keywords

  • Laser retinopexy
  • macular hole
  • macular hole closure
  • vitreomacular adhesion

ASJC Scopus subject areas

  • Ophthalmology

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