What Research Questions Should the Next Generation of Birth Cohort Studies Address? An International Delphi Study of Experts

Ruth Harriet Brown*, Manuel Eisner, Sara Valdebenito, Susan Walker, Mark Tomlinson, Claire Hughes, Catherine L. Ward, Joseph Osafo, Siham Sikander, Pasco Fearon, Michael P. Dunne, Bernadette Madrid, Adriana Baban, Vo Van Thang, Asvini D. Fernando, Aja L. Murray

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Objective: Birth cohort studies (BCS) have generated a wealth of invaluable basic scientific and policy-relevant information on a wide range of issues in child health and development. This study sought to explore what research questions are currently a priority for the next generation of BCS using a 3-round Delphi survey of interdisciplinary experts. Methods: Twenty-four (Round I, N = 17; Round II, N = 21; Round III, N = 18) experts across a wide range of fields (eg, psychology, public health, and maternal/child health) agreed to participate. In Round I, the expert panel was invited to freely respond to the question, “what are the key scientific questions future birth cohort studies should address?” Content analysis of answers was used to identify 47 questions for rating on perceived importance by the panel in Round II and consensus-achieving questions were identified. Questions that did not reach consensus in Round II were posed again for expert re-rating in Round III. Results: Twenty six of 47 questions reached consensus in Round II, with an additional 6 reaching consensus in Round III. Consensus-achieving questions rated highly on importance spanned a number of topics, including environmental effects on child development, intergenerational transmission of disadvantage, and designing BCS to inform intervention strategies. Conclusion: Investigating the effects of family/environmental factors and social disadvantage on a child's development should be prioritized in designing future BCS. The panel also recommended that future BCS are designed to inform intervention strategies.

Original languageEnglish
Pages (from-to)43-52
Number of pages10
JournalAcademic Pediatrics
Volume21
Issue number1
Early online date31 Dec 2020
DOIs
Publication statusPublished - Jan 2021

Bibliographical note

Funding Information:
Financial statement: This work was supported by the Global Challenges Research Fund (grant number: GCRF01 ).

Funding Information:
We are grateful to the University of Edinburgh College of Arts, Humanities and Social Sciences SFA ODA Global Challenges Fund for funding the current research. In addition, we are grateful to Dr Charlotte Hanlon, Dr Jena Hamadani, Professor Edmund Sonuga-Barke, Professor Guenther Fink, Dr Inácio Crochmore, Professor Jane Fisher, Professor Lynne Murray, Professor Kathy Sylva, Dr Santiago Cueto, Professor Theresa Betancourt, and the other anonymous experts who formed our expert panel.

Publisher Copyright:
© 2020

Keywords

  • birth cohort studies
  • consensus
  • Delphi method
  • research priorities

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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