Abstract
A growing body of evidence indicates that obesity is strongly and independently associated with adverse outcomes of COVID-19, including death. By combining emerging knowledge of the pathological processes involved in COVID-19 with insights into the mechanisms underlying the adverse health consequences of obesity, we present some hypotheses regarding the deleterious impact of obesity on the course of COVID-19. These hypotheses are testable and could guide therapeutic and preventive interventions. As obesity is now almost ubiquitous and no vaccine for COVID-19 is currently available, even a modest reduction in the impact of obesity on mortality and morbidity from this viral infection could have profound consequences for public health.
Original language | English |
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Pages (from-to) | 33-42 |
Journal | Med |
Volume | 1 |
Issue number | 1 |
Early online date | 25 Jun 2020 |
DOIs | |
Publication status | Published - 18 Dec 2020 |
Externally published | Yes |