WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity

Fatemeh Mirzadeh Azad, Yaser Atlasi

Research output: Contribution to journalArticlepeer-review

Abstract

Enhancer reprogramming lies at the heart of dynamic cellular processes such as differentiation and tumorigenesis. WNT signaling is an evolutionary conserved pathway that exploits transcriptional enhancers to control the state-specific transcriptional program. Recent evidences suggest several mechanisms that govern this state-specific enhancer regulation in stem cells and cancer.
Original languageEnglish
JournalTrends in Cell Biology
Early online date25 Mar 2021
DOIs
Publication statusEarly online date - 25 Mar 2021

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