WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity

Fatemeh Mirzadeh  Azad; Yaser Atlasi

doi:10.1016/j.tcb.2021.03.007

WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity

Fatemeh Mirzadeh Azad
, Yaser Atlasi

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Enhancer reprogramming lies at the heart of dynamic cellular processes such as differentiation and tumorigenesis. WNT signaling is an evolutionary conserved pathway that exploits transcriptional enhancers to control the state-specific transcriptional program. Recent evidences suggest several mechanisms that govern this state-specific enhancer regulation in stem cells and cancer.

Original language	English
Pages (from-to)	525-528
Number of pages	4
Journal	Trends in Cell Biology
Volume	31
Issue number	7
Early online date	10 Jun 2021
DOIs	https://doi.org/10.1016/j.tcb.2021.03.007
Publication status	Published - 01 Jul 2021

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title = "WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity",

abstract = "Enhancer reprogramming lies at the heart of dynamic cellular processes such as differentiation and tumorigenesis. WNT signaling is an evolutionary conserved pathway that exploits transcriptional enhancers to control the state-specific transcriptional program. Recent evidences suggest several mechanisms that govern this state-specific enhancer regulation in stem cells and cancer.",

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AU - Atlasi, Yaser

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AB - Enhancer reprogramming lies at the heart of dynamic cellular processes such as differentiation and tumorigenesis. WNT signaling is an evolutionary conserved pathway that exploits transcriptional enhancers to control the state-specific transcriptional program. Recent evidences suggest several mechanisms that govern this state-specific enhancer regulation in stem cells and cancer.

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DO - 10.1016/j.tcb.2021.03.007

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WNT-Regulated Transcriptional Enhancers and Stem Cell Plasticity

Abstract

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