An investigation of Soluplus® as a polymeric carrier for manufacture of amorphous solid dispersions: pre-screening, dissolution behaviour and formulation development of drug enabled delivery systems

Jincheng Yang

School of Pharmacy

Student thesis: Doctoral Thesis › Doctor of Philosophy

Abstract

Thesis embargoed until 31st December 2028

Date of Award	Dec 2023
Original language	English
Awarding Institution	Queen's University Belfast
Supervisor	Shu Li (Supervisor), Valentyn Mohylyuk (Supervisor) & Gavin Andrews (Supervisor)

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Research output
Increasing thermal stability of Albendazole by compounding with Soluplus
Research output: Contribution to conference › Poster › peer-review
The dissolution of albendazole and felodipine from Kollidon VA64® and Soluplus® based amorphous solid dispersions
Research output: Contribution to conference › Poster › peer-review
Effect of Preparation Method and Method Conditions on the Stability of High Drug-Loaded (60% w/w) Amorphous Solid Dispersion (ASD) of Felodipine-Soluplus®
Research output: Contribution to conference › Poster › peer-review
Effect of thermal and thermal-mechanical treatment on the albendazole degradation
Research output: Contribution to conference › Poster › peer-review
Effect of Soluplus® and its concentration on the precipitation of Albendazole and Felodipine: Screening the ‘parachute’ effect
Research output: Contribution to conference › Poster › peer-review
The enhancement of the aqueous solubility of Albendazole employing polymeric amorphous solid dispersion (ASD) as an approach
Research output: Contribution to conference › Poster › peer-review
The Effects of Differential Scanning Calorimetry Conditions on the Determined Solubility of Felodipine in Soluplus
Research output: Contribution to conference › Poster › peer-review

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