Temporal analysis of clinico-pathological variables and biomarkers in cancer

  • Sophia Halliday

Student thesis: Doctoral ThesisDoctor of Philosophy

Abstract

Blood biomarkers are commonly used in many cancers to help diagnose disease or predict survival. However, these biomarkers are often dichotomised to facilitate easy analysis and interpretation. This categorisation removes a vast amount of information, particularly either side of the enforced boundaries, which otherwise could give improved insights into the prognosis of individuals. This research focuses on using blood biomarkers measured at diagnosis, pre-treatment and post-treatment, in continuous form, to develop prognostic models in prostate (PCa) and oesophageal (OAC) cancers.
Date of AwardDec 2019
Original languageEnglish
Awarding Institution
  • Queen's University Belfast
SupervisorJaine Blayney (Supervisor) & Richard Kennedy (Supervisor)

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