Former organisational unit. 30/04/2016. Taken over by Centre for Experimental Medicine

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      1. 2017
      2. Early online date

        Characterisation of eppin function: expression and activity in the lung

        Scott, A., Glasgow, A., Small, D., Carlile, S., McCrudden, M., McLean, D., Brown, R., Doherty, D., Lundy, F., Hamid, U., O'Kane, C., McAuley, D., Brodlie, M., Tunney, M., Elborn, J., Irwin, C., Timson, D., Taggart, C. & Weldon, S. 01 Jul 2017 In : European Respiratory Journal. 50, 1, 11 p., 1601937. , 1601937

        Research output: Research - peer-reviewArticle

      3. Early online date

        Antibody-induced internalization of the human respiratory syncytial virus fusion protein

        Leemans, A., De Schryver, M., Van der Gucht, W., Heykers, A., Pintelon, I., Hotard, A. L., Moore, M. L., Melero, J. A., McLellan, J. S., Graham, B., Broadbent, L., Power, U. F., Caljon, G., Cos, P., Maes, L. & Delputte, P. 03 May 2017 In : Journal of Virology.

        Research output: Research - peer-reviewArticle

      4. Early online date

        Tropical ulcer plant treatments used by Papua New Guinea's Apsokok nomads

        Prescott, T. A. K., Homot, P., Lundy, F. T., Patrick, S., Cámara-Leret, R. & Kiapranis, R. 03 May 2017 In : Journal of Ethnopharmacology. 205, p. 240-245 6 p.

        Research output: Research - peer-reviewArticle

      5. Published
      6. Published

        The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia

        Mohamed, Y. F., Hamad, M., Ortega, X. P. & Valvano, M. A. Apr 2017 In : Molecular Microbiology. 104, 1, p. 144-162

        Research output: Research - peer-reviewArticle

      7. Published

        Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells.

        Omar, S., Clarke, R., Abdullah, H., Brady, C., Corry, J., Winter, H., Touzelet, O., Power, U. F., Lundy, F., McGarvey, L. P. A. & Cosby, S. L. Feb 2017 In : PLoS One. 12, 2, 21 p., e0171681. , e0171681

        Research output: Research - peer-reviewArticle

      8. Published

        High-volume haemofiltration for sepsis in adults

        Borthwick, E. M., Hill, C. J., Rabindranath, K. S., Maxwell, A. P., McAuley, D. F. & Blackwood, B. 31 Jan 2017 In : The Cochrane database of systematic reviews. 1, 42 p., CD008075. , CD008075

        Research output: Research - peer-reviewArticle

      9. Published

        Interventions to prevent steroid-induced osteoporosis and osteoporotic fractures in Duchenne muscular dystrophy (Review)

        Bell, J. M., Shields, M., Watters, J., Hamilton, A., Beringer, T., Elliott, M., Quinlivan, R., Tirupathi, S. & Blackwood, B. 24 Jan 2017 In : Cochrane database of systematic reviews (Online). 1, CD010899. , CD010899

        Research output: Research - peer-reviewArticle

      10. Published

        Bacterial proteases and haemostasis dysregulation in the CF lung

        Reihill, J. A., Moreland, M., Jarvis, G. E., McDowell, A., Einarsson, G. G., Elborn, J. S. & Martin, S. L. Jan 2017 In : Journal of Cystic Fibrosis. 16, 1, p. 49-57 9 p.

        Research output: Research - peer-reviewArticle

      11. Published

        Long-term general and cardiovascular safety of tiotropium/olodaterol in patients with moderate to very severe chronic obstructive pulmonary disease

        Buhl, R., Magder, S., Bothner, U., Tetzlaff, K., Voß, F., Loaiza, L., Vogelmeier, C. F. & McGarvey, L. Jan 2017 In : Respiratory Medicine. 122, p. 58-66 9 p.

        Research output: Research - peer-reviewArticle

      12. 2016
      13. Published

        TNFAIP3 (TUMOUR NECROSIS FACTOR, APLHA-INDUCED PROTEIN 3)

        Schock, B., Ennis, M. & McElroy, R. 26 Dec 2016 A20_Tumor Necrosis Factor Alpha induced protein 3 (TNFAIP3).

        Research output: Research - peer-reviewChapter (peer-reviewed)

      14. Published
      15. Published
      16. Published

        A comparison of different pre-lysis methods and extraction kits for recovery of Stretococcus agalacticae (Lancefield group B Streptococcus) DNA from whole blood

        Burke, R. M., McKenna, J. P., Cox, C., Coyle, P. V., Shields, M. D. & Fairley, D. J. Oct 2016 In : Journal of Microbiological Methods. 129, p. 103-108 6 p.

        Research output: Research - peer-reviewArticle

      17. Early online date
      18. Published

        Physical rehabilitation interventions for adult patients during critical illness: an overview of systematic reviews

        Connolly, B., Brenda, O. N., Salisbury, L. & Blackwood, B. 14 Sep 2016 In : Thorax. 71, 11 p.

        Research output: Research - peer-reviewArticle

      19. Published

        Inhibition of protease-ENaC signaling improves mucociliary function in cystic fibrosis airways

        Reihill, J. A., Walker, B., Hamilton, R. A., Ferguson, T. E. G., Elborn, J. S., Stutts, M. J., Harvey, B. J., Saint-Criq, V., Hendrick, S. M. & Martin, S. L. Sep 2016 In : American Journal of Respiratory and Critical Care Medicine. 194, 6, p. 701-710 10 p.

        Research output: Research - peer-reviewArticle

      20. Published

        Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis

        Barnard, E., Liu, J., Yankova, E., Cavalcanti, S. M., Magalhães, M., Li, H., Patrick, S. & McDowell, A. 24 Aug 2016 In : Scientific reports. 6, 9 p., 31968. , 31968

        Research output: Research - peer-reviewArticle

      21. Published

        Chronic inflammation in CF airways - a persistent issue for A20

        McCollum, K., El Banna, A., Ennis, M. & Schock, B. 19 Aug 2016 In : Journal of Genetic Syndromes & Gene Therapy .

        Research output: Research - peer-reviewArticle

      22. Published

        Community dynamics and the lower airway microbiota in stable chronic obstructive pulmonary disease, smokers and healthy non-smokers

        Einarsson, G. G., Comer, D. M., McIlreavey, L., Parkhill, J., Ennis, M., Tunney, M. M. & Elborn, J. S. 12 Aug 2016 In : Thorax. 71, p. 795-803

        Research output: Research - peer-reviewArticle

      23. Published

        Efficacy and safety of lumacaftor/ivacaftor combination therapy in patients with cystic fibrosis homozygous for Phe508del CFTR by pulmonary function subgroup

        VX-809 TRAFFIC Study group & TRANSPORT Study Group Aug 2016 In : The Lancet Respiratory Medicine. 4, 8, p. 617-626

        Research output: Research - peer-reviewArticle

      24. Published

        In Vitro modelling of RSV infection and cytopathogenesis in well-differentiated human primary airway epithelial cells (WD-PAECs).

        Broadbent, L., Villenave, R., Guo Parke, H., Douglas, I., Shields, M. & Power, U. Aug 2016 Methods in Molecular Biology. Springer, Vol. 1442, p. 119-139 21 p.

        Research output: ResearchChapter

      25. Published

        Structural and Functional Lung Impairment in Adult Survivors of Bronchopulmonary Dysplasia

        Caskey, S., Gough, A., Rowan, S., Gillespie, S., Clarke, J., Riley, M., Megarry, J., Nicholls, P., Patterson, C., Halliday, H. L., Shields, M. D. & McGarvey, L. Aug 2016 In : Annals of the American Thoracic Society. 13, 8, p. 1262-1270 9 p.

        Research output: Research - peer-reviewArticle

      26. Published

        Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

        Bousquet, J., Farrell, J., Crooks, G., Hellings, P., Bel, E. H., Bewick, M., Chavannes, N. H., de Sousa, J. C., Cruz, A. A., Haahtela, T., Heaney, L. G. & Shields, M. 29 Jul 2016 In : Clinical and translational allergy. 6, p. 29

        Research output: Research - peer-reviewArticle

      27. Published

        Effectiveness of a biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use: protocol for a randomised controlled trial (VAPrapid-2): Study protocol for a randomised controlled trial

        Hellyer, T. P., Anderson, N. H., Parker, J., Dark, P., van den Broeck, T., Singh, S., McMullan, R., Agus, A., Emerson, L. M., Blackwood, B., Gossain, S., Walsh, T., Perkins, G., Conway Morris, A., McAuley, D. F. & Simpson, A. J. 16 Jul 2016 In : Trials. 17, 1, 8 p., 318. , 318

        Research output: Research - peer-reviewArticle

      28. Early online date

        Lung clearance index in adults and children with cystic fibrosis

        O'Neill, K., Tunney, M. M., Johnston, E., Rowan, S., Downey, D., Rendall, J., Reid, A., Bradbury, I., Elborn, J. S. & Bradley, J. M. 06 Jul 2016 In : Chest. 150, 6, p. 1323-1332 10 p.

        Research output: Research - peer-reviewArticle

      29. Published

        Low-pathogenicity Mycoplasma spp. alter human monocyte and macrophage function and are highly prevalent among patients with ventilator-acquired pneumonia

        Nolan, T. J., Gadsby, N. J., Hellyer, T. P., Templeton, K. E., McMullan, R., McKenna, J., Rennie, J., Robb, C. T., Walsh, T. S., Rossi, A. G., Conway Morris, A. & Simpson, A. J. 01 Jul 2016 In : Thorax. 71, 7, p. 594-600 7 p.

        Research output: Research - peer-reviewArticle

      30. Published

        Technological aids for the rehabilitation of memory and executive functioning in children and adolescents with acquired brain injury (Review).

        Linden, M., Hawley, C., Blackwood, B., Evans, J., Anderson, V. & O'Rourke, C. 01 Jul 2016 In : Cochrane Database of Systematic Reviews. 2016, 7, 51 p., CD011020. , CD011020

        Research output: Research - peer-reviewArticle

      31. Published

        Behavior change theory, content and delivery of interventions to enhance adherence in chronic respiratory disease: A systematic review

        McCullough, A. R., Ryan, C., Macindoe, C., Yii, N., Bradley, J. M., O'Neill, B., Elborn, J. S. & Hughes, C. M. Jul 2016 In : Respiratory Medicine. 116, p. 78-84 7 p.

        Research output: Research - peer-reviewArticle

      32. Published

        Lipopolysaccharide modification in Gram-negative bacteria during chronic infection

        Maldonado, R. F., Sá-Correia, I. & Valvano, M. Jul 2016 In : FEMS Microbiol. Rev.. 40, 4, p. 480-493 14 p.

        Research output: Research - peer-reviewArticle

      33. Published

        Connectivity Mapping (ssCMap) To Predict A20 Inducing Drugs: Anti-inflammatory Action In Cystic Fibrosis

        Malcomson, B., Wilson, H., Thillaiyampalan, G., Barsden, R., Donegan, S., El Banna, A., Elborn, J., Ennis, M., Kelly, C., Zhang, S-D. & Schock, B. 28 Jun 2016 In : Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. E3725–E3734 10 p.

        Research output: Research - peer-reviewArticle

      34. Published

        Fetal umbilical artery Doppler pulsatility index and childhood neurocognitive outcome at 12 years

        Mone, F., McConnell, B., Thompson, A., Segurado, R., Hepper, P., Stewart, M. C., Dornan, J. C., Ong, S., McAuliffe, F. M. & Shields, M. D. 15 Jun 2016 In : BMJ Open. 6, 6

        Research output: Research - peer-reviewArticle

      35. Published

        Antimicrobial activity of a novel liposomal azithromycin formulation against clinical CF respiratory isolates

        Bashi, Y. D., Payne, J., McGrath, S. J., Elborn, J. S., Tunney, M. M. & Kett, V. L. Jun 2016 In : Journal of Cystic Fibrosis. 15, S1, p. S49 1 p., ePs06.6. , ePs06.6

        Research output: Research - peer-reviewMeeting abstract

      36. Published

        Cigarettes, e-cigarettes and Pseudomonas aeruginosa: Interactions in the CF lung?

        McGown, K-A., Bengoechea, J., Dumigan, A., Elborn, J. S., Tunney, M. M. & Gilpin, D. Jun 2016 In : Journal of Cystic Fibrosis. 15, Supplement 1, p. S65 1 p.

        Research output: Research - peer-reviewMeeting abstract

      37. Published

        Susceptibility of Staphylococcus aureus isolates from patients with and without cystic fibrosis to ceftobiprole

        Gilpin, D., Carson, G., Lee, A., McGrath, S., Elborn, J. S. & Tunney, M. M. Jun 2016 In : Journal of Cystic Fibrosis. 15, S1, p. S83-S84 2 p., 129. , 129

        Research output: Research - peer-reviewMeeting abstract

      38. Published

        Microbial Regulation of Gastrointestinal Immunity in Health and Disease

        Patrick, S., Ingram, R., Schneiders, T. & Fitzgerald, D. 25 May 2016 Neuro-Immuno-Gastroenterology. Constantinescu, C., Arsenescu, R. & Arsenescu, V. (eds.). Springer, p. 39-52 14 p.

        Research output: Research - peer-reviewChapter (peer-reviewed)

      39. Published

        A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome

        Aubert, D. F., Xu, H., Yang, J., Shi, X., Gao, W., Li, L., Bisaro, F., Chen, S., Valvano, M. A. & Shao, F. 11 May 2016 In : Cell host & microbe. 19, 5, p. 664-674 11 p.

        Research output: Research - peer-reviewArticle

      40. Published

        Correction: Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

        De Majumdar, S., Yu, J., Fookes, M., McAteer, S. P., Llobet, E., Spence, S. F. S., Monaghan, A., Kissenpfennig, A., Ingram, R. J., Bengoechea, J., Gally, D. L., Fanning, S., Elborn, J. S. & Schneiders, T. 11 May 2016 In : PLoS Pathogens. 12, 5, p. e1005649

        Research output: Research - peer-reviewArticle

      41. Published

        EGFR interacts with the fusion protein of respiratory syncytial virus strain 2-20 and mediates infection and mucin expression.

        Currier, M. G., Lee, S., Stobart, C. C., Hotard, A. L., Villenave, R., Meng, J., Pretto, C., Shields, M. D., Nguyen, M. T., Todd, S. O., Chi, M. H., Hammonds, J., Krumm, S. A., Spearman, P., Plemper, R. K., Sakamoto, K., Peebles, R. S., Power, U. F. & Moore, M. L. 06 May 2016 In : PLoS Pathogens. 12, 5

        Research output: Research - peer-reviewArticle

      42. Published
      43. Published

        A Secretory Leukocyte Protease Inhibitor Variant with Improved Activity against Lung Infection

        Camper, N., Glasgow, A. M. A., Osbourn, M., Quinn, D. J., Small, D. M., McLean, D. T., Lundy, F. T., Elborn, J. S., McNally, P., Ingram, R. J., Weldon, S. & Taggart, C. C. May 2016 In : Mucosal Immunology. 9, 3, p. 669-676

        Research output: Research - peer-reviewArticle

      44. Published

        Genomic meningococcal load in the nasopharynx of children with meningococcal disease

        Bourke, T. W., McKenna, J. P., Coyle, P. V., Fairley, D. J. & Shields, M. D. May 2016 In : The Pediatric Infectious Disease Journal. 35, 5, p. 577-579

        Research output: Research - peer-reviewArticle

      45. Published

        Parents’ and young people’s involvement in designing a trial of ventilator weaning

        Tume, L. N., Preston, J. & Blackwood, B. May 2016 In : Nursing in Critical Care. 21, 3, p. e10-e18

        Research output: Research - peer-reviewArticle

      46. Early online date
      47. Early online date

        Acute Respiratory Distress Syndrome

        Mac Sweeney, R. & McAuley, D. F. 28 Apr 2016 In : Lancet. 15 p.

        Research output: Research - peer-reviewArticle

      48. Published

        Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

        Cruickshank, M., Henderson, L., MacLennan, G., Fraser, C., Campbell, M., Blackwood, B., Gordon, A. & Brazzelli, M. Apr 2016 In : Health Technology Assessment. 20, 25, p. 1-118 118 p.

        Research output: Research - peer-reviewArticle

      49. Published

        Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells

        El Karim, I. A., McCrudden, M. T. C., McGahon, M. K., Curtis, T. M., Jeanneau, C., Giraud, T., Irwin, C. R., Linden, G. J., Lundy, F. T. & About, I. Apr 2016 In : Journal of Endodontics. 42, 4, p. 589-595 7 p.

        Research output: Research - peer-reviewArticle

      50. Published

        MRSA eradication of newly acquired lower respiratory tract infection in cystic fibrosis

        Vallières, E., Rendall, J. C., Moore, J. E., McCaughan, J., Hoeritzauer, A. I., Tunney, M. M., Elborn, J. S. & Downey, D. G. 31 Mar 2016 In : ERJ Open. 2, 1, 00064-2015. , 00064-2015

        Research output: Research - peer-reviewArticle

      51. Published

        STAT3 activation in circulating monocytes contributes to neovascular age-related macular degeneration

        Chen, M., Lechner, J., Zhao, J., Toth, L., Hogg, R., Silvestri, G., Kissenpfennig, A., Chakravarthy, U. & Xu, H. 24 Mar 2016 In : Current Molecular Medicine. 16, 4, p. 412-423 12 p.

        Research output: Research - peer-reviewArticle

      52. Published

        Prevotella denticola Lipopolysaccharide from a Cystic Fibrosis Isolate Possesses a Unique Chemical Structure

        Di Lorenzo, F., Silipo, A., Matier, T., Hanuszkiewicz, A., Elborn, J. S., Lanzetta, R., Sturiale, L., Scamporrino, A., Garozzo, D., Valvano, M. A., Tunney, M. M. & Molinaro, A. 23 Mar 2016 In : European Journal of Organic Chemistry. 2016, 9, p. 1732-1738 7 p.

        Research output: Research - peer-reviewArticle

      53. Published

        Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants: review

        Wielenga, J. M., van den Hoogen, A., van Zanten, H. A., Helder, O., Bol, B. & Blackwood, B. 21 Mar 2016 In : Cochrane Database of Systematic Reviews. 3, 18 p., CD011106. , CD011106

        Research output: Research - peer-reviewArticle

      54. Early online date

        Night-to-night variation of pulse oximetry in children with sleep-disordered breathing

        Burke, R. M., Maxwell, B., Hunter, C., Graham, D., O'Donoghue, D. & Shields, M. D. 11 Mar 2016 In : Archives of Disease in Childhood.

        Research output: Research - peer-reviewArticle

      55. Published

        Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry

        Sweeney, J., Patterson, C. C., Menzies-Gow, A., Niven, R. M., Mansur, A. H., Bucknall, C., Chaudhuri, R., Price, D., Brightling, C. E. & Heaney, L. G. Mar 2016 In : Thorax. 71, 4, p. 339-346 8 p.

        Research output: Research - peer-reviewArticle

      56. Published
      57. Published

        Closed circuit rebreathing to achieve inert gas wash-in for multiple breath wash-out

        Horsley, A. R., O'Neill, K., Downey, D. G., Elborn, J. S., Bell, N. J., Smith, J. & Owers-Bradley, J. 09 Feb 2016 In : ERJ Open. 2, 1, 8 p.

        Research output: Research - peer-reviewArticle

      58. Early online date

        Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation

        Moazed, F., Burnham, E. L., Vandivier, R. W., O'Kane, C. M., Shyamsundar, M., Hamid, U., Abbott, J., Thickett, D. R., Matthay, M. A., McAuley, D. F. & Calfee, C. S. 02 Feb 2016 In : Thorax. 8 p.

        Research output: Research - peer-reviewArticle

      59. Published

        Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness

        Scott, J., Harris, G. J., Pinder, E. M., Macfarlane, J. G., Hellyer, T. P., Rostron, A. J., Conway Morris, A., Thickett, D. R., Perkins, G. D., McAuley, D. F., Widdrington, J. D., Wiscombe, S., Baudouin, S. V., Roy, A. I., Linnett, V. C., Wright, S. E., Ruchaud-Sparagano, M. H. & Simpson, A. J. 01 Feb 2016 In : The Journal of allergy and clinical immunology. 137, 2, p. 535-544 10 p.

        Research output: Research - peer-reviewArticle

      60. Published

        Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells

        Reihill, J. A., Malcomson, B., Bertelsen, A., Cheung, S., Czerwiec, A., Barsden, R., Elborn, J. S., Dürkop, H., Hirsch, B., Ennis, M., Kelly, C. & Schock, B. C. Feb 2016 In : British Journal of Pharmacology. 173, 4, p. 778-789 12 p.

        Research output: Research - peer-reviewArticle

      61. Published
      62. Published

        Tolerance to sedative drugs in PICU: Can it be moderated or is it immutable?

        Wolf, A. R., Blackwood, B. & Anderson, B. Feb 2016 In : Intensive Care Medicine. 42 , 2, p. 278–281 4 p.

        Research output: Research - peer-reviewArticle

      63. Early online date
      64. Early online date

        The common vaginal commensal bacterium Ureaplasma parvum is associated with chorioamnionitis in extreme preterm labour

        Cox, C., Saxena, N., Watt, A. P., Gannon, C., McKenna, J. P., Fairley, D. J., Sweet, D., Shields, M. D., Cosby, S. L. & Coyle, P. V. 22 Jan 2016 In : The Journal of Maternal-Fetal & Neonatal Medicine. 15 p.

        Research output: Research - peer-reviewArticle

      65. Published

        Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report

        Gibson, P., Wang, G., McGarvey, L., Vertigan, A. E., Altman, K. W. & Birring, S. S. 06 Jan 2016 In : Chest. 149, 1, p. 27-44 18 p.

        Research output: Research - peer-reviewArticle

      66. Published
      67. Published

        Asthma control and exacerbations: two different sides of the same coin.

        Heaney, L. G. & Brisk, R. 01 Jan 2016 In : Current Opinon in Pulmonary Medicine. 22, 1, p. 32-37 6 p.

        Research output: Research - peer-reviewArticle

      68. Published

        CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor

        Ascough, S., Ingram, R. J., Chu, K. K. Y., Musson, J. A., Moore, S. J., Gallagher, T., Baillie, L., Williamson, E. D., Robinson, J. H., Maillere, B., Boyton, R. J. & Altmann, D. M. Jan 2016 In : Frontiers in Microbiology. 6, 12 p., 1506. , 1506

        Research output: Research - peer-reviewArticle

      69. Published

        Exhaled breath temperature measurement and asthma control in children prescribed inhaled corticosteroids: A cross sectional study

        Hamill, L., Ferris, K., Kampande, K., McConaghy, L., Douglas, I., McGovern, V. & Shields, M. D. Jan 2016 In : Pediatric Pulmonology. 51, 1, p. 13-21 9 p.

        Research output: Research - peer-reviewArticle

      70. Published

        Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

        Detalle, L., Stohr, T., Palomo, C., Piedra, P. A., Gilbert, B. E., Mas, V., Millar, A., Power, U. F., Stortelers, C., Allosery, K., Melero, J. A. & Depla, E. Jan 2016 In : Antimicrobial Agents and Chemotherapy. 60, 1, p. 6-13 8 p.

        Research output: Research - peer-reviewArticle

      71. Published

        Interferon-γ stimulates CD14, TLR2 and TLR4 mRNA expression in gingival fibroblasts increasing responsiveness to bacterial challenge

        Lappin, M. J., Brown, V., Zaric, S. S., Lundy, F. T., Coulter, W. A. & Irwin, C. R. Jan 2016 In : Archives of Oral Biology. 61, p. 36-43 8 p.

        Research output: Research - peer-reviewArticle

      72. Published

        Response to letter by Popov, Todor regarding our paper: Exhaled breath temperature measurement and asthma control in children prescribed inhaled corticosteroids: A cross sectional study

        Hamill, L., Ferris, K., Kapande, K., Mcconaghy, L., Douglas, I., Mcgovern, V. & Shields, M. D. Jan 2016 In : Pediatric Pulmonology. 51, 1, p. 93 1 p.

        Research output: ResearchLetter

      73. Published

        Altered lung microbiota profiles are associated with disease severity, exacerbation frequency and neutrophilic inflammation in bronchiectasis: B16. CYSTIC FIBROSIS (CF) AND NON-CF BRONCHIECTASIS

        Dicker, A. J., Fong, C., Crichton, M., Cassidy, A., Suarez-Cuartin, G., Sibila, O., Einarsson, G. G., Ibrahim, W., Elborn, J. S. & Palmer, C. N. A. 2016 p. A2879-A2879

        Research output: Research - peer-reviewAbstract

      74. Published

        ArnT proteins that catalyse the glycosylation of lipopolysaccharide share common features with bacterial N-oligosaccharyltransferases

        Tavares-Carreón, F., Mohamed, Y. F., Andrade, A. & Valvano, M. A. 2016 In : Glycobiology. 26, 3, p. 286-300 15 p.

        Research output: Research - peer-reviewArticle

      75. Forthcoming

        Breaking ground; year 2

        Ingram, R. & Barnett-Vanes, A. 2016 (Accepted) How to complete a PhD in the medical and clinical sciences. Wiley-Blackwell

        Research output: ResearchChapter

      76. Published
      77. Published

        Mannose Binding Lectin Deficient Haplotypes Are Associated With Fewer Exacerbations And A More Diverse Microbiome In Chronic Obstructive Pulmonary Disease: A21. CHRONIC AIRWAY INFLAMMATION: MICROBIAL INFLUENCE

        Dicker, A. J., Crichton, M., Cassidy, A., Brady, G., Hapca, A., Einarsson, G. G., Elborn, J. S., Schembri, S., Marshall, S. & Palmer, C. N. A. 2016 p. A1075-A1075

        Research output: Research - peer-reviewAbstract

      78. Published

        Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epithelium

        Boxio, R., Wartelle, J., Nawrocki-Raby, B., Lagrange, B., Malleret, L., Hirche, T., Taggart, C., Pacheco, Y., Devouassoux, G. & Bentaher, A. 2016 In : Respiratory Research. 17, 15 p., 129. , 129

        Research output: Research - peer-reviewArticle

      79. Published

        Reduced epithelial suppressor of cytokine signalling 1 in severe eosinophilic asthma

        Doran, E., Choy, D. F., Shikotra, A., Butler, C. A., O'Rourke, D. M., Johnston, J. A., Kissenpfennig, A., Bradding, P., Arron, J. R. & Heaney, L. G. 2016 In : European Respiratory Journal. 48, 3, p. 715-725 11. , 11

        Research output: Research - peer-reviewArticle

      80. Published

        WS07. 4 Effect of ivacaftor on airway bacterial community composition in CF patients with the G551D mutation

        Mooney, D., Ronan, N. J., Einarsson, G., Flanagan, E. T., Eustace, J. A., Tunney, M. M., Elborn, J. S. & Plant, B. J. 2016 p. S12

        Research output: Research - peer-reviewAbstract

      81. 2015
      82. Published

        A single chromosome assembly of Bacteroides fragilis strain BE1 from Illumina and MinION nanopore sequencing data

        Risse, J., Thomson, M., Patrick, S., Blakely, G., Koutsovoulos, G., Blaxter, M. & Watson, M. 04 Dec 2015 In : GigaScience. 4, 1, 7 p., 60. , 60

        Research output: Research - peer-reviewArticle

      83. Published

        Eight International London Cough Symposium 2014: Cough hypersensitivity syndrome as the basis for chronic cough

        Chung, K. F., Canning, B. & McGarvey, L. Dec 2015 In : Pulmonary pharmacology & therapeutics. 35, p. 76-80 5 p.

        Research output: Research - peer-reviewArticle

      84. Published

        Induction and antagonism of antiviral responses in respiratory syncytial virus-infected pediatric airway epithelium.

        Villenave, R., Broadbent, L., Douglas, I., Lyons, J. D., Coyle, P. V., Teng, M. N., Tripp, R. A., Heaney, L. G., Shields, M. D. & Power, U. F. Dec 2015 In : Journal of Virology. 89, 24, p. 12309-12318 10 p.

        Research output: Research - peer-reviewArticle

      85. Published

        Lack of Association Between Haptoglobin Phenotype and Cystic Fibrosis Outcomes

        Shteinberg, M., Rivlin, J., Gur, M., Konopnicki, M., Stein, N., Tunney, M. M., Elborn, J. S., Downey, D. G., Johnston, E., Shalom, H. & Levy, A. Dec 2015 In : Lung. 193, 6, p. 1017-1021 5 p.

        Research output: Research - peer-reviewArticle

      86. Published

        Primary airway epithelial cell culture and asthma in children-lessons learnt and yet to come

        McLellan, K., Shields, M., Power, U. & Turner, S. Dec 2015 In : Pediatric Pulmonology. 50, 12, p. 1393-1405 13 p.

        Research output: Research - peer-reviewArticle

      87. Published

        Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination

        Natrajan, M. S., de la Fuente, A. G., Crawford, A. H., Linehan, E., Nunez, V., Johnson, K. R., Wu, T., Fitzgerald, D., Ricote, M., Bielekova, B. & Franklin, R. J. M. Dec 2015 In : Brain. 138, 12, p. 3581-3597

        Research output: Research - peer-reviewArticle

      88. Published

        Tyrosine phosphorylation and dephosphorylation in Burkholderia cenocepacia affect biofilm formation, growth under nutritional deprivation, and pathogenicity

        Andrade, A., Tavares-Carreon, F., Khodai-Kalaki, M. & Valvano, M. A. 20 Nov 2015 In : Applied and Environmental Microbiology. 82, 3, p. 843 856 p.

        Research output: Research - peer-reviewArticle

      89. Published
      90. Published

        Respiratory alterations and management

        Wetzig, S., Blackwood, B. & Currey, J. 12 Nov 2015 ACCCN's Critical Care Nursing . Aitken, L., Marshall, A. & Chaboyer, W. (eds.). 3rd ed. Chatswood, NSW, Australia: Elsevier, p. 438-469

        Research output: ResearchChapter

      91. Published

        Interaction of Arenicin-1 with C1q Protein

        Berlov, M. N., Umnyakova, E. S., Leonova, T. S., Milman, B. L., Krasnodembskaya, A. D., Ovchinnikova, T. V. & Kokryakov, V. N. 01 Nov 2015 In : BIOORGANICHESKAYA KHIMIYA. 41, 6, p. 664-668 5 p.

        Research output: Research - peer-reviewArticle

      92. Published

        Quantification of Type VI secretion system activity in macrophages infected with Burkholderia cenocepacia

        Aubert, D. F., Hu, S. & Valvano, M. A. 01 Nov 2015 In : Microbiology. 161, 11, p. 2161-2173 46 p.

        Research output: Research - peer-reviewArticle

      93. Published

        Challenges of harmonising data from UK national health surveys: a case study of attempts to estimate the UK prevalence of asthma

        Nwaru, B. I., Mukherjee, M., Gupta, R. P., Farr, A., Heaven, M., Stoddart, A., Bandyopadhyay, A., Fitzsimmons, D., Shields, M., Phillips, C., Chamberlain, G., Fischbacher, C., Dibben, C., Aftab, C., Simpson, C. R., Lyons, R., Strachan, D., Davies, G. A., McKinstry, B. & Sheikh, A. Nov 2015 In : Journal of the Royal Society of Medicine. 108, ., p. 433-439 7 p.

        Research output: Research - peer-reviewArticle

      94. Published

        Clinical Evaluation of Streptococcus pneumoniae Polymerase Chain Reaction in Children with Suspected Septicemia

        Bourke, T. W., Fairley, D. J., McKenna, J. P., Coyle, P. V. & Shields, M. D. Nov 2015 In : The Pediatric Infectious Disease Journal. 34, 11, p. 1276-7 2 p.

        Research output: ResearchLetter

      95. Published
      96. Published
      97. Published

        Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome

        Toner, P., McAuley, D. F. & Shyamsundar, M. 23 Oct 2015 In : Critical Care. 19, 1, 9 p., 374. , 374

        Research output: Research - peer-reviewArticle

      98. Published
      99. Published

        Drug therapies in severe asthma - the era of stratified medicine

        Hetherington, K. J. & Heaney, L. 05 Oct 2015 In : Clinical medicine (London, England). 15, 5, p. 452-456

        Research output: Research - peer-reviewArticle

      100. Published

        Phenotypic characterization of an international Pseudomonas aeruginosa reference panel: strains of cystic fibrosis (CF) origin show less in vivo virulence than non-CF strains

        Cullen, L. , Weiser, R. , Olszak, T. , Maldonado, R. F. , Moreira, A. S. , Slachmuylders, L. , Brackman, G. , Paunova-Krasteva, T. S. , Zarnowiec, P. , Czerwonka, G. , Reilly, J. , Drevinek, P. , Kaca, W. , Melter, O. , de Soyza, A. , Perry, A. , Winstanley, C. , Stoitsova, S. R. , Lavigne, R. , Mahenthiralingam, E. & 6 others Sá-Correia, I., Coenye, T., Drulis-Kawa, Z., Augustyniak, D., Valvano, M. A. & McClean, S. 01 Oct 2015 In : Microbiology. 161, 10, p. 1961-1977 17 p.

        Research output: Research - peer-reviewArticle

      101. Published

        Dedicated severe asthma services improve health-care use and quality of life

        Gibeon, D., Heaney, L. G., Brightling, C. E., Niven, R., Mansur, A. H., Chaudhuri, R., Bucknall, C. E. & Menzies-Gow, A. N. Oct 2015 In : Chest. 148, 4, p. 870-876 7 p.

        Research output: Research - peer-reviewArticle

      102. Published

        Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia

        Loutet, S. A., El-Halfawy, O. M., Jassem, A. N., Sánchez López, J. M., Fernández Medarde, A., Speert, D. P., Davies, J. E. & Valvano, M. A. Oct 2015 In : International Journal of Antimicrobial Agents. 46, 4, p. 376-380 5 p.

        Research output: Research - peer-reviewArticle

      103. Published

        Lung Clearance Index in cystic fibrosis subjects treated for Pulmonary Exacerbations

        Sonneveld, N. I., Stanojevic, S., Amin, R., Aurora, P., Davies, J., Elborn, S., Horsley, A., Latzin, P., O'Neill, K., Robinson, P., Scrase, E., Selvadurai, H., Subbarao, P., Welsh, L., Yammine, S. & Ratjen, F. Oct 2015 In : European Respiratory Journal. 46, 4, p. 1055-1064 10 p.

        Research output: Research - peer-reviewArticle

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