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    Research Statement

    The overarching aim of my research is to understand the lymphocytic response to bacterial infections, in order to facilitate rational vaccine design. I have a particular interest in the interface between innate and adaptive lymphocytic cell responses.  We use a combination of approaches to elucidate the lymphocytic responses to bacterial infection, including in vitro models and analysis of clinical samples, but the greatest area of expertise within my lab is the use of in vivo murine bacterial infection models.  There are a number of ongoing projects within the lab, these include;

    (i) The induction of innate immunological memory against bacterial infection.

    (ii) Identification of bacterial (Pseudomonas and Anthrax) antigens that elicit a memory T cell response and may therefore represent novel vaccine candidates

    (iii) Defining the role of T cells in driving and resolving inflammation (Streptococcus and Pseudomonas)

    (iv) The rational design and optimisation of pre-clinical models to test novel antimicrobials and investigate host-pathogen interactions. 

    Frequent Journals

    • PLoS Pathogens

      ISSNs: 1553-7366

      Additional searchable ISSN (Electronic): 1553-7374

      Public Library of Science

      Scopus rating (2017): CiteScore 6.05 SJR 4.006 SNIP 1.548

      Journal

    • Journal of Immunology

      ISSNs: 0022-1767

      Additional searchable ISSN (Electronic): 1550-6606

      American Association of Immunologists

      Scopus rating (2017): CiteScore 4.55 SJR 2.837 SNIP 1.112

      Journal

    • Frontiers in Microbiology

      ISSNs: 1664-302X

      Additional searchable ISSN (Electronic): 1664-302X

      Frontiers Media S.A.

      Scopus rating (2017): CiteScore 4.19 SJR 1.699 SNIP 1.174

      Journal

    • American Journal of Respiratory and Critical Care Medicine

      ISSNs: 1073-449X

      Additional searchable ISSN (Electronic): 1535-4970

      American Thoracic Society

      Scopus rating (2017): CiteScore 5.1 SJR 5.942 SNIP 2.998

      Journal

    • Infection and Immunity

      ISSNs: 0019-9567

      American Society for Microbiology

      Scopus rating (2017): CiteScore 3.43 SJR 1.954 SNIP 0.953

      Journal

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    Contribution to conference papers, events and activities

    ID: 53572