Bernadette McGuinness

    Bernadette McGuinness

    Clinical Senior Lecturer

    Phone: +44 (0)28 9097 8959

    For media contact email comms.office@qub.ac.uk
    or call +44(0)2890 973091.

    Scopus Citations 148

    1. 2019
    2. Published

      The role of dry EEG in a memory clinic setting: a delayed recognition task

      Toogood, A., Fitzpatrick, P., McCartney, B., Murphy, B., Jurek-Loughrey, A., Devereux, B. & McGuinness, B., 14 Jul 2019.

      Research output: Contribution to conferenceAbstract

    3. Published
    4. Published
    5. Published

      The feasibility of mobile-EEG to profile cognitive impairment in Parkinson's disease and early-stage dementia

      Sweeney, A., Devereux, B., Kearney, S., McKinley, J., Ong, C. W., Anderson, J., Murphy, B., McGuinness, B. & Passmore, A., 14 Apr 2019.

      Research output: Contribution to conferenceAbstract

    6. Early online date
    7. Published

      Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery

      Pan, X., Cunningham, E. L., Passmore, A. P., McGuinness, B., McAuley, D. F., Beverland, D., O'Brien, S., Mawhinney, T., Schott, J. M., Zetterberg, H. & Green, B. D., 12 Mar 2019, In : Scientific Reports. 9, 1, 9 p., 4191., 4191

      Research output: Contribution to journalArticle

    8. 2018
    9. Published
    10. Published

      Effect of dietary interventions in mild cognitive impairment: a systematic review

      McGrattan, A., McEvoy, C., McGuinness, B., McKinley, M. & Woodside, J., 09 Nov 2018, In : British Journal of Nutrition. 120, p. 1388 1405 p.

      Research output: Contribution to journalArticle

    11. Published

      Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology

      Bin Nasaruddin, M., Pan, X., McGuinness, B., Passmore, A., Kehoe, P. G., Holscher, C., Graham, S. & Green, B., 26 Oct 2018, In : Metabolites. 8, 4

      Research output: Contribution to journalArticle

    12. Published
    13. Published
    14. Published

      Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

      Tedja, M. S., Wojciechowski, R., Hysi, P. G., Eriksson, N., Furlotte, N. A., Verhoeven, V. J. M., Iglesias, A. I., Meester-Smoor, M. A., Tompson, S. W., Fan, Q., Khawaja, A. P., Cheng, C. Y., Höhn, R., Yamashiro, K., Wenocur, A., Grazal, C., Haller, T., Metspalu, A., Wedenoja, J., Jonas, J. B. & 30 othersWang, Y. X., Xie, J., Mitchell, P., Foster, P. J., Klein, B. E. K., Klein, R., Paterson, A. D., Hosseini, S. M., Shah, R. L., Williams, C., Teo, Y. Y., Tham, Y. C., Gupta, P., Zhao, W., Shi, Y., Saw, W. Y., Chen, W., Evans, D. M., Wang, J. J., Wilson, C. H., Blows, P., Chakravarthy, U., Hogg, R. E., McGaughey, M., McGuinness, B., McKay, G. J., Paterson, E. N., Peto, T., Woodside, J. V. & Simpson, C. L., 01 Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

      Research output: Contribution to journalArticle

    15. Published
    16. Published

      Automated quantification of retinal vessel morphometry in the UK biobank cohort

      on behalf of the UK Biobank Eye and Vision Consortium, 12 Mar 2018, Proceedings of the 7th International Conference on Image Processing Theory, Tools and Applications (IPTA 2017). Institute of Electrical and Electronics Engineers Inc., 6 p. (International Conference on Image Processing Theory, Tools and Applications (IPTA): Proceedings).

      Research output: Chapter in Book/Report/Conference proceedingConference contribution

    17. Published
    18. Early online date

      CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study

      Cunningham, E. L., McGuinness, B., McAuley, D. F., Toombs, J., Mawhinney, T., O'Brien, S., Beverland, D., Schott, J. M., Lunn, M. P., Zetterberg, H. & Passmore, A. P., 02 Feb 2018, In : Annals of Surgery.

      Research output: Contribution to journalArticle

    19. 2017
    20. Early online date
    21. Early online date
    22. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

      ARUK Consortium, 17 Jul 2017, In : Nature Genetics. 49, 9, p. 1373-1384

      Research output: Contribution to journalArticle

    23. Published

      Metabolomic Profiling of Bile Acids in Clinical and Experimental Samples of Alzheimer's Disease

      Pan, X., Elliott, C. T., McGuinness, B., Passmore, P., Kehoe, P. G., Hölscher, C., McClean, P. L., Graham, S. F. & Green, B. D., 17 Jun 2017, In : Metabolites. 7, 2, 12 p., 28., 28

      Research output: Contribution to journalArticle

    24. Early online date
    25. Published

      Pisa syndrome due to donepezil: pharmacokinetic interactions to blame?

      Pollock, D., Cunningham, E., McGuinness, B. & Passmore, A. P., 24 Jan 2017, In : Age and Ageing. 46, 3, p. 529-530 2 p.

      Research output: Contribution to journalArticle

    26. Published

      Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

      Barber, I. S., Braae, A., Clement, N., Patel, T., Guetta-Baranes, T., Brookes, K., Medway, C., Chappell, S., Guerreiro, R., Bras, J., Hernandez, D., Singleton, A. B., Hardy, J., Mann, D. M., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R. & 16 othersKölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Pickering-Brown, S., Snowden, J., Richardson, A., Jones, M., Neary, D., Harris, J., Lowe, J., Smith, A. D., Wilcock, G., Warden, D., Holmes, C. & Morgan, K., 01 Jan 2017, In : Neurobiology of Aging. 49, p. 215.e1-215.e8

      Research output: Contribution to journalArticle

    27. 2016
    28. Published

      ABCA7 p.G215S as potential protective factor for Alzheimer's disease

      Sassi, C., Nalls, M. A., Ridge, P. G., Gibbs, J. R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Clement, N., Lord, J., Turton, J., Bras, J., Almeida, M. R., Passmore, P., Craig, D., Johnston, J., McGuinness, B. & 30 othersTodd, S., Heun, R., Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Mann, D. M., Pickering-Brown, S., Brown, K. S., Lowe, J., Morgan, K., Smith, A. D., Wilcock, G., Warden, D., Holmes, C., Holstege, H., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Van Swieten, J. C., Santana, I., Oliveira, C., Morgan, K., Powell, J. F., Kauwe, J. S. K., Cruchaga, C., Goate, A. M., Singleton, A. B., Guerreiro, R. & Hardy, J., 01 Oct 2016, In : Neurobiology of Aging. 46, p. 235.e1-235.e9

      Research output: Contribution to journalArticle

    29. Published

      Platelet membrane ß-secretase activity in mild cognitive impairment and conversion to dementia: a longitudinal study.

      McGuinness, B., Fuchs, M., Barrett, S. L., Passmore, A. P. & Johnston, J. A., 01 Oct 2016, In : Journal of Alzheimer's disease : JAD. 49, 4, p. 1095-1103 9 p.

      Research output: Contribution to journalArticle

    30. Early online date
    31. Early online date

      A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol

      Greenan, C., Murphy, L., Yu, L-M., Kehoe, P. G., Coulthard, E., Bath, P., Stewart, R., Jones, R., Corbett, A., Thomas, A., Connelly, P., Arrojo, F., Canning, R., Wallach, S., Henderson, C., McGuinness, B., O'Sullivan, M., Holmes, C., Knapp, M., Ballard, C. & 2 othersPassmore, P. & AFFECT Investigators, 18 Jul 2016, In : Trials. 17, 324, 12 p.

      Research output: Contribution to journalArticle

    32. Published

      Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer’s Disease

      Sassi, C., Ridge, P. G., Nalls, M. A., Gibbs, R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Lord, J., Turton, J., Morgan, K., Powell, J. F., Kauwe, J. S. K., Cruchaga, C., Bras, J., Goate, A. M., Singleton, A. B. & 18 othersGuerreiro, R., Hardy, J., Passmore, P., Craig, D., Johnston, J., McGuinness, B., Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Mann, D. M., Lowe, J., David Smith, A., Wilcock, G., Warden, D. & Holmes, C., 01 Jun 2016, In : PLoS ONE. 11, 6, e0150079., e0150079

      Research output: Contribution to journalArticle

    33. Published

      Automated retinal image quality assessment on the UK Biobank dataset for epidemiological studies

      UK Biobank Eye and Vision Consortium, 01 Apr 2016, In : Computers in Biology and Medicine. 71, p. 67-76 10 p.

      Research output: Contribution to journalArticle

    34. Published

      Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease

      Barber, I. S., Garc??a-C??rdenas, J. M., Sakdapanichkul, C., Deacon, C., Zapata Erazo, G., Guerreiro, R., Bras, J., Hernandez, D., Singleton, A. B., Guetta-Baranes, T., Braae, A., Clement, N., Patel, T., Brookes, K., Medway, C., Chappell, S., Mann, D. M., Passmore, P., Craig, D., Johnston, J. & 19 othersMcGuinness, B., Todd, S., Heun, R., Kolsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Pickering-Brown, S., Snowden, J., Richardson, A., Jones, M., Neary, D., Harris, J., Lowe, J., Smith, A. D., Wilcock, G., Warden, D., Holmes, C. & Morgan, K., 01 Mar 2016, Neurobiology of Aging. Elsevier Inc., p. 220.e1-220.e7 (Neurobiology of Aging; vol. 39).

      Research output: Chapter in Book/Report/Conference proceedingChapter

    35. Published

      Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease.

      Traylor, M., Adib-Samii, P., Harold, D., Alzheimer's Disease Neuroimaging Initiative, T. A. D. N., International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource, T. I. S. G. C., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., METASTROKE, H. S., International Genomics of Alzheimer's Project (IGAP), investigators, A. T. METASTROKE. A. I. G. O. A. P. IGAP., Fornage, M., Holliday, E. G., Sharma, P., Bis, J. C., Psaty, B. M., Seshadri, S., Nalls, M. A., Devan, W. J., Boncoraglio, G. & 155 othersMalik, R., Mitchell, B. D., Kittner, S. J., Ikram, M. A., Clarke, R., Rosand, J., Meschia, J. F., Sudlow, C., Rothwell, P. M., Levi, C., Bevan, S., Kilarski, L. L., Walters, M., Thijs, V., Slowik, A., Lindgren, A., de Bakker, P. I. W., Lambert, J-C., Ibrahim-Verbaas, C. A., Harold, D., Naj, A. C., Sims, R., Bellenguez, C., Jun, G., DeStefano, A. L., Bis, J. C., Beecham, G. W., Grenier‐Boley, B., Russo, G., Thornton‐Wells, T. A., Jones, N., Smith, A. V., Chouraki, V., Thomas, C., Ikram, M. A., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, CF., Gerrish, A., Schmidt, H., Kunkle, B., Dunstan, M. L., Ruiz, A., Bihoreau, MT., Choi, S-H., Reitz, C., Pasquier, F., Hollingworth, P., Ramirez, A., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Baldwin, C., Becker, T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., Jager, P. L. D., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Morón, F. J., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiçvet, N., Huentelman, M. J., Gill, M., Brown, K. S., Kamboh, M. I., Keller, L., Barberger‐Gateau, P., McGuinness, B., Larson, E. B., Green, R., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., George‐Hyslop, P. S., Clarimon, J., Lleo, A., Bayer, A. J., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez‐Garcia, F., Fox, N. C., Hardy, J., Naranjo, M. C. D., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Mancuso, M., Matthews, F. E., (EADI), E. A. D. I., (GERAD), G. A. E. R. I. A. D., (ADGC), A. D. G. C., (CHARGE), C. F. H. A. A. R. I. G. E., Moebus, S., Mecocci, P., Zompo, M. D., Maier, W., Hampel, H., Pilotto, A., Bullido, M., Panza, F., Caffarra, P., Nacmias, B., Gilbert, J. R., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton‐Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S. & Mosley, T. H., 23 Feb 2016, Annals of neurology. Wiley-Blackwell, p. 739 1 p. (Annals of neurology; vol. 79).

      Research output: Chapter in Book/Report/Conference proceedingChapter

    36. Published

      Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome

      Pan, X., Bin Nasaruddin, M., Elliott, C. T., McGuinness, B., Passmore, A. P., Kehoe, P. G., Holscher, C., McClean, P. L., Graham, S. F. & Green, B. D., Feb 2016, In : Neurobiology of Aging. 38, p. 151-163 13 p.

      Research output: Contribution to journalArticle

    37. 2015
    38. Published
    39. Published

      Convergent genetic and expression data implicate immunity in Alzheimer's disease

      Jones, L., Lambert, J-C., Wang, L-S., Choi, S-H., Harold, D., Vedernikov, A., Escott-Price, V., Stone, T., Richards, A., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Gerrish, A., Craig, D., Johnston, J. A., McGuinness, B., Todd, S. & Passmore, P., Jun 2015, In : Alzheimers & dementia. 11, 6, p. 658-671 14 p.

      Research output: Contribution to journalArticle

    40. Published

      Dementia

      Cunningham, E. L., McGuinness, B., Herron, B. & Passmore, A. P., May 2015, In : Ulster Medical Journal. 84, 2, p. 79-87

      Research output: Contribution to journalArticle

    41. Published

      Reciting the months of the year backwards: what is a 'normal' score?

      Cunningham, EL., Passmore, AP., McAuley, DF. & McGuinness, B., May 2015, In : Age and Ageing. 44, 3, p. 537-538 2 p.

      Research output: Contribution to journalArticle

    42. Published

      Blood type gene locus has no influence on ACE association with Alzheimer's disease

      Braae, A., Medway, C., Carrasquillo, M., Younkin, S., Alzheimer's Research UK (ARUK) Consortium, Kehoe, P. G., Morgan, K., Passmore, P., Craig, D., Johnston, J. & McGuinness, B., 01 Apr 2015, In : Neurobiology of Aging. 36, 4, p. 1767.e1-1767.e2

      Research output: Contribution to journalArticle

    43. Published
    44. Published

      Longitudinal examination of the blood and brain metabolome of the APP/PS1 mouse.

      Pan, X., Bin Nasaruddin, M., Elliott, C., McGuinness, B., Passmore, A., Kehoe, P. G., Holscher, C., McClean, P., Graham, S. & Green, B., 11 Mar 2015.

      Research output: Contribution to conferenceAbstract

    45. Published

      Aspirin and anti-inflammatory drugs for the prevention of dementia

      Jordan, F., McGuinness, B., Murphy, K., Passmore, P., Kelly, J. P. & Devane, D., 08 Jan 2015, In : Cochrane Database of Systematic Reviews. 2015, 1, p. 1-12

      Research output: Contribution to journalArticle

    46. Published
    47. 2014
    48. Published

      Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

      Proitsi, P., Lupton, M. K., Velayudhan, L., Hunter, G., Newhouse, S., Lin, K., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Craig, D., Todd, S., Johnston, J. A., McGuinness, B., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Passmore, P. A., Sims, R. & 6 othersWilliams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S. & Powell, J. F., Dec 2014, In : Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p.

      Research output: Contribution to journalArticle

    49. Published

      Age-Associated Changes of Brain Copper, Iron, and Zinc in Alzheimer's Disease and Dementia with Lewy Bodies

      Graham, S. F., Nasaruddin, M. B., Carey, M., Holscher, C., McGuinness, B., Kehoe, P. G., Love, S., Passmore, P., Elliott, C. T., Meharg, A. A. & Green, B. D., 13 Oct 2014, In : Journal of Alzheimer's disease : JAD. 42, 4, p. 1407-1413

      Research output: Contribution to journalArticle

    50. Published

      Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

      Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Harold, D., Sims, R., Gerrish, A., Chapman, J., Escott-Price, V., Abraham, R., Hollingworth, P. & 74 othersHamshere, M., Singh Pahwa, J., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Williams, K., Lovestone, S., Powell, J. F., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P., Craig, D., Mcguinness, B., Johnston, J. A., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Guerreiro, R., Singleton, A. B., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Nöthen, M. M., Holmans, P. A., O'Donovan, M. C., Owen, M. J., Williams, J., Stewart, R. C. & Sham, P., 16 Sep 2014, In : PLoS Medicine. 11, 9

      Research output: Contribution to journalArticle

    51. Published

      Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease.

      Cruchaga, C., Karch, CM., Jin, SC., Benitez, BA., Cai, Y., Guerrera, R., Harari, O., Norton, J., Budde, J., Bertelsen, S., Jeng, AT., Cooper, B., Skorupa, T., Carrell, D., Levitz, D., Hsu, S., Choi, J., Ryten, M., Hardy, J., Trabzuni, D. & 61 othersWeale, ME., Ramasami, A., Smith, C., Sassy, C., Bras, J., Gibbs, JR., Hernandez, DG., Lupton, MK., Powell, J., Forabosco, P., Ridge, PG., Corcoran, CD., Tschanz, JT., Norton, MC., Munger, RG., Schmutz, C., Leary, M., Demirci, FY., Bamne, MN., Wang, X., Lopez, OL., Ganguli, M., Medway, C., Turton, J., Lord, J., Braae, A., Barber, I., Brown, K., Passmore, A., Craig, D., Todd, S., Johnston, J., McGuinness, B., Heun, R., Kolsch, H., Kehoe, PG., Hooper, NM., Wilcock, G., Vardy, ER., Mann, DM., Pickering-Brown, S., Kalsheker, N., Lowe, J., Morgan, K., Smith, D., Warden, D., Holmes, C., Pastor, P., Lorenzo-Betancor, O., Brkanac, Z., Scott, E., Topol, E., Rogaeva, E., Singleton, AB., Hardy, J., Kamboh, MI., St George-Hyslop, P., Cairns, N., Morris, JC., Kauwe, JS. & Goate, A., 23 Jan 2014, In : Nature. 505, p. 550-554 5 p.

      Research output: Contribution to journalArticle

    52. 2013
    53. Published

      Plasma Clusterin Levels and the rs11136000 Genotype in Individuals with Mild Cognitive Impairment and Alzheimer's Disease

      Mullan, G. M., McEneny, J., Fuchs, M., McMaster, C., Todd, S., McGuinness, B., Henry, M., Passmore, A. P., Young, I. S. & Johnston, J. A., Nov 2013, In : Current Alzheimer Research. 10, 9, p. 973-978 6 p.

      Research output: Contribution to journalArticle

    54. Published
    55. 2012
    56. Published

      Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

      Proitsi, P., Lupton, M. K., Dudbridge, F., Tsolaki, M., Hamilton, G., Daniilidou, M., Pritchard, M., Lord, K., Martin, B. M., Craig, D., Todd, S., McGuinness, B., Hollingworth, P., Harold, D., Kloszewska, I., Soininen, H., Mecocci, P., Velas, B., Gill, M., Lawlor, B. & 6 othersRubinsztein, D. C., Brayne, C., Passmore, P. A., Williams, J., Lovestone, S. & Powell, J. F., Aug 2012, In : Neurobiology of Aging. 33, 8, p. 1843.e9-17

      Research output: Contribution to journalArticle

    57. Published

      Cochrane review on 'Statins for the treatment of dementia'

      McGuinness, B., O'Hare, J., Craig, D., Bullock, R., Malouf, R. & Passmore, P., 2012, In : International Journal of Geriatric Psychiatry.

      Research output: Contribution to journalArticle

    58. Forthcoming

      Encouraging behaviour change in mild cognitive impairment patients: development of educational material.

      Neville, C., McCourt, H., McKinley, M., Lowis, C., Barrett, S., McGuinness, B., Todd, S., Lawlor, B., Gibb, M., Coen, R., Passmore, P. & Woodside, J., 2012, (Accepted).

      Research output: Contribution to conferencePaper

    59. Published

      Genetic variation in MME in relation to neprilysin protein and enzyme activity, Aβ levels, and Alzheimer's disease risk

      Miners, S., van Helmond, Z., Barker, R., Passmore, P. A., Johnston, J. A., Todd, S., McGuinness, B. M., Panza, F., Seripa, D., Solfrizzi, V., Love, S., Prince, J. A. & Kehoe, P. G., 2012, In : International journal of molecular epidemiology and genetics. 3, 1, p. 30-8 9 p.

      Research output: Contribution to journalArticle

    60. Published

      The development of effective biomarkers for Alzheimer's disease: a review

      Henry, M. S., Passmore, A. P., Todd, S., McGuinness, B., Craig, D. & Johnston, J. A., 2012, In : International Journal of Geriatric Psychiatry.

      Research output: Contribution to journalArticle

    61. Published

      The Role of Variation at AβPP, PSEN1, PSEN2, and MAPT in Late Onset Alzheimer's Disease

      Gerrish, A., Russo, G., Richards, A., Moskvina, V., Ivanov, D., Harold, D., Sims, R., Abraham, R., Hollingworth, P., Chapman, J., Hamshere, M., Pahwa, J. S., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J. & 73 othersProitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Johnston, J. A., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Kölsch, H., Heun, R., Schürmann, B., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Davies, G., Harris, S. E., Starr, J. M., Deary, I. J., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Mühleisen, T. W., Nöthen, M. M., Moebus, S., Jöckel, K-H., Klopp, N., Wichmann, H-E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Jones, L., Holmans, P. A., O'Donovan, M. C., Owen, M. J., Williams, J. & Morgan, K., 2012, In : Journal of Alzheimer's disease : JAD. 28, 2, p. 377-87 11 p.

      Research output: Contribution to journalArticle

    62. 2011
    63. Published

      Genome-wide association study of Alzheimer's disease with psychotic symptoms

      Hollingworth, P., Sweet, R., Sims, R., Harold, D., Russo, G., Abraham, R., Stretton, A., Jones, N., Gerrish, A., Chapman, J., Ivanov, D., Moskvina, V., Lovestone, S., Priotsi, P., Lupton, M., Brayne, C., Gill, M., Lawlor, B., Lynch, A., Craig, D. & 22 othersMcGuinness, B., Johnston, J., Holmes, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Holmans, P., Jones, L., Devlin, B., Klei, L., Barmada, M. M., Demirci, F. Y., Dekosky, S. T., Lopez, O. L., Passmore, P., Owen, M. J., O'Donovan, M. C., Mayeux, R., Kamboh, M. I., Williams, J. & the GERAD Consortium, 18 Oct 2011, In : Molecular Psychiatry.

      Research output: Contribution to journalArticle

    64. Published

      Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

      Hollingworth, P., Harold, D., Sims, R., Gerrish, A., Lambert, J. C., Carrasquillo, M. M., Abraham, R., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Jones, N., Stretton, A., Thomas, C., Richards, A., Ivanov, D., Widdowson, C., Chapman, J., Lovestone, S., Powell, J. & 152 othersProitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Brown, K. S., Passmore, P., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Beaumont, H., Warden, D., Wilcock, G., Love, S., Kehoe, P. G., Hooper, N. M., Vardy, E. R. L. C., Hardy, J., Mead, S., Fox, N. C., Rossor, M., Collinge, J., Maier, W., Jessen, F., Ruther, E., Schurmann, B., Heun, R., Kolsch, H., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frolich, L., Hampel, H., Gallacher, J., Hull, M., Rujescu, D., Giegling, I., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Muhleisen, T. W., Nothen, M. M., Moebus, S., Jockel, K. H., Klopp, N., Wichmann, H. E., Pankratz, V. S., Sando, S. B., Aasly, J. O., Barcikowska, M., Wszolek, Z. K., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Van Duijn, C. M., Breteler, M. M. B., Ikram, M. A., DeStefano, A. L., Fitzpatrick, A. L., Lopez, O., Launer, L. J., Seshadri, S., Berr, C., Campion, D., Epelbaum, J., Dartigues, J. F., Tzourio, C., Alperovitch, A., Lathrop, M., Feulner, T. M., Friedrich, P., Riehle, C., Krawczak, M., Schreiber, S., Mayhaus, M., Nicolhaus, S., Wagenpfeil, S., Steinberg, S., Stefansson, H., Stefansson, K., Snaedal, J., Bjornsson, S., Jonsson, P. V., Chouraki, V., Genier-Boley, B., Hiltunen, M., Soininen, H., Combarros, O., Zelenika, D., Delepine, M., Bullido, M. J., Pasquier, F., Mateo, I., Frank-Garcia, A., Porcellini, E., Hanon, O., Coto, E., Alvarez, V., Bosco, P., Siciliano, G., Mancuso, M., Panza, F., Solfrizzi, V., Nacmias, B., Sorbi, S., Bossu, P., Piccardi, P., Arosio, B., Annoni, G., Seripa, D., Pilotto, A., Scarpini, E., Galimberti, D., Brice, A., Hannequin, D., Licastro, F., Jones, L., Holmans, P. A., Jonsson, T., Riemenschneider, M., Morgan, K., Younkin, S. G., Owen, M. J., O'Donovan, M., Amouyel, P. & Williams, J., May 2011, In : Nature Genetics. 43, 5, p. 429-35 7 p.

      Research output: Contribution to journalArticle

    65. Published

      A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD)

      Proitsi, P., Hamilton, G., Tsolaki, M., Lupton, M., Daniilidou, M., Hollingworth, P., Archer, N., Foy, C., Stylios, F., McGuinness, B., Todd, S., Lawlor, B., Gill, M., Brayne, C., Rubinsztein, D. C., Owen, M., Williams, J., Craig, D., Passmore, P., Lovestone, S. & 1 othersPowell, J. F., Mar 2011, In : Neurobiology of Aging. 32, 3, p. 434-442 9 p.

      Research output: Contribution to journalArticle

    66. Published

      A multi-center study of ACE and the risk of late-onset Alzheimer's disease

      Belbin, O., Brown, K., Shi, H., Medway, C., Abraham, R., Passmore, P., Mann, D., Smith, A. D., Holmes, C., McGuinness, B., Craig, D., Warden, D., Heun, R., Kölsch, H., Love, S., Kalsheker, N., Williams, J., Owen, M. J., Carrasquillo, M., Younkin, S. & 2 othersKehoe, P. G. & Morgan, K., 2011, In : Journal of Alzheimer's disease : JAD. 24, 3, p. 587-97 11 p.

      Research output: Contribution to journalArticle

    67. Published
    68. 2010
    69. Published

      Apolipoprotein epsilon4 and neuropsychological performance in Alzheimer's disease and vascular dementia

      McGuinness, B., Carson, R., Barrett, S., Craig, D. & Passmore, P., Oct 2010, In : Neuroscience Letters. 483, 1, p. 62-66 5 p.

      Research output: Contribution to journalArticle

    70. Published

      Northern Ireland Dementia Strategy

      Todd, S., Wilson, D., McGuinness, B., Craig, D. & Passmore, P., Sep 2010, In : International Journal of Geriatric Psychiatry. 25, 9, p. 902-904 3 p.

      Research output: Contribution to journalArticle

    71. Published

      Executive functioning in Alzheimer's disease and vascular dementia

      McGuinness, B., Barrett, S. L., Craig, D., Lawson, J. & Passmore, A. P., Jun 2010, In : International Journal of Geriatric Psychiatry. 25, 6, p. 562-568 7 p.

      Research output: Contribution to journalArticle

    72. Published

      Attention deficits in Alzheimer's disease and vascular dementia

      McGuinness, B., Barrett, S., Craig, D., Lawson, J. & Passmore, P., Feb 2010, In : Journal of neurology, neurosurgery, and psychiatry. 81, 2, p. 157-159 3 p.

      Research output: Contribution to journalArticle

    73. Published
    74. Published

      Inflammation and Anti-inflammatory strategies for alzheimer disease a mini review

      McNaull, B. B. A., Todd, S., McGuinness, B. & Passmore, A. P., Jan 2010, In : Gerontology. 56, 1, p. 3-14 12 p.

      Research output: Contribution to journalArticle

    75. Published

      Can statins prevent or help treat Alzheimer's disease?

      McGuinness, B. & Passmore, P., 2010, In : Journal of Alzheimer's Disease. 20, 3, p. 925-933 9 p.

      Research output: Contribution to journalArticle

    76. Published

      Designing appropriate clincial trials to assess ACEI use and cognitive decline in older adults with hypertension

      Todd, S., McGuinness, B. & Passmore, P., 2010, Arch Intern Med : Unknown Publisher.

      Research output: Other contribution

    77. Published

      Statins for the treatment of dementia

      McGuinness, B., O'Hare, J., Craig, D., Bullock, R., Malouf, R. & Passmore, P., 2010, In : Cochrane Database of Systematic Reviews. 4, 8, p. CD007514

      Research output: Contribution to journalArticle

    78. 2009
    79. Published

      Variation in RTN3 and PPIL2 Genes Does not Influence Platelet Membrane β-Secretase Activity or Susceptibility to Alzheimer’s Disease in the Northern Irish Population

      Carson, R., McKnight, A. J., Todd, S., Liu, W. W., Heggarty, S., Craig, D., McGuinness, B., Irvine, G. B., Passmore, A. P. & Johnston, J. A., Dec 2009, In : NeuroMolecular Medicine. 11, 4, p. 337-344 8 p.

      Research output: Contribution to journalArticle

    80. Published

      A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets.

      Liu, W., Todd, S., Coulson, D., Irvine, B., Passmore, P., McGuinness, B., McConville, M., Craig, D. & Johnston, J., Jan 2009, In : Journal of Neurochemistry. 108, 2, p. 341-349 9 p.

      Research output: Contribution to journalArticle

    81. Published

      How useful is dual energy lateral vertebral assessment in a clinic setting?

      McGuinness, B., Stewart, S. & Taggart, H., Jan 2009, In : The Ulster Medical Journal. 78, 1, p. 34-6 3 p.

      Research output: Contribution to journalArticle

    82. Published
    83. Published

      Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia Review

      McGuinness, B., Todd, S., Passmore, P. & Bullock, R., 2009, The Cochrane Library : Unknown Publisher.

      Research output: Other contribution

    84. Published

      Reduced estimated glomerular filtration rate in Alzheimer's disease

      Craig, D., McGuinness, B., Dynan, K. B., Fogarty, D., Johnston, J., Passmore, P. & Kerr, E., 2009, In : International Journal of Geriatric Psychiatry. 24, 9, p. 927-932 6 p.

      Research output: Contribution to journalArticle

    85. Published

      Statins for the prevention of dementia

      McGuinness, B., Craig, D., Bullock, R. & Passmore, P., 2009, In : Cochrane Database of Systematic Reviews. null, 2, CD003160., CD003160

      Research output: Contribution to journalArticle

    86. 2008
    87. Published

      BACE1 Polymorphisms Do Not Influence Platelet Membrane β-secretase Activity or Genetic Susceptibility for Alzheimer’s Disease in the Northern Irish Population

      Todd, S., McKnight, A. J., Liu, W. W., Carson, R., Heggarty, S., McGuinness, B., Irvine, G. B., Craig, D., Passmore, A. P. & Johnston, J. A., Dec 2008, In : NeuroMolecular Medicine. 10, 4, p. 368-376 9 p.

      Research output: Contribution to journalArticle

    88. Published

      Alpha7 nicotinic acetylcholine receptor gene and reduced risk of Alzheimer's disease.

      Craig, D., McGuinness, B., Johnston, J., O'Neill, F., Passmore, P. & Ritchie, C. W., Apr 2008, In : Journal of Medical Genetics. 45, 4, p. 244-248 5 p.

      Research output: Contribution to journalArticle

    89. 2007
    90. Published

      Beneficial cognitive effects of treating hypertension are not clear

      Craig, D., McGuinness, B., Todd, S., Passmore, P. & Bullock, R., Jun 2007

      Research output: Non-textual formWeb publication/site