Chen Situ

    Dr Chen Situ

    Lecturer

    Phone: +44 (0)28 9097 6546

    For media contact email comms.office@qub.ac.uk
    or call +44(0)2890 973091.

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    Research Interests

    • AMR - developmet of plant-based antimicroial alternatives
    • Health and disease in humans and animals
    • Food safety, quality and nutrition
    • Rapid immunodiagnostic for chemical contaminants and biomarkers

    Antimicrobial resistance (AMR) is a huge threat encompassing health and economic burdens in every region of the globe. Overuse or misuse of antibiotics can accelerate the natural evolution of microorganisms and the associated consequence has been further implicated by the lack of development of new antibiotics over the past 40 years. Responsible use of antibiotics and development of antibiotic alternatives are paramount in combatting AMR.

    Traditional herbal medicine, sustained by near 7000 years of anecdotal theory and practice, still remains as major healthcare systems in many parts of the world and is very different from the mainstream of western medicine. My research interest in this area focuses on the development of plant-based phytochemicals as safer and sustainable alternative to therapeutic antibiotics for use in humans and animals. Over the past 12 years, we have developed in-house expertise spanning from initial screening to isolation and identification of bio-compound, as well as toxicity evaluation and mode of action study to decipher the traditional knowledge of herbal remedy. We will collaborate with other research institution and industry (pharmaceutical, food and nutritional) to explore both therapeutic and health potential of botanicals as antimicrobial agents for tackling AMR, as nutraceuticals for promoting health and general well-being in humans, and as natural supplements for enhancing health and productivity of food animals.

    My other research lies in the development of immunochemical and molecular methods utilising a range of biotechnological platforms including SPR biosensor and nanotechnology. I have actively participated with major roles in a series of EU Framework Programme projects (FP4-FP7) since 1998 and developed a range of commercial diagnostic kits for detection of small and large molecules such as antibiotic residues, chemicals proteins and biomarkers. More recently, I coordinated a PF7 international collaborative project with over €1M EC funding to develop immuno- and physicochemical methods for the detection of recombinant bovine growth hormone (Unique-Check, 2009-2013) with academic and industrial partners from Belgium, France and UK.  

    Frequent Journals

    • Analytica Chimica Acta

      ISSNs: 0003-2670

      Additional searchable ISSN (Electronic): 1873-4324

      Elsevier B.V.

      Scopus rating (2018): SJR 1.467 SNIP 1.386

      Journal

    • Planta Medica

      ISSNs: 0032-0943

      Additional searchable ISSN (Electronic): 1439-0221

      Georg Thieme Verlag

      Scopus rating (2018): SJR 0.559 SNIP 1.024

      Journal

    • Food Analytical Methods

      ISSNs: 1936-9751

      Additional searchable ISSN (Electronic): 1936-976X

      Springer New York

      Scopus rating (2018): SJR 0.688 SNIP 0.894

      Journal

    • Foods

      Additional searchable ISSN (Electronic): 2304-8158

      Multidisciplinary Digital Publishing Institute (MDPI)

      Journal

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    Contribution to conference papers, events and activities

    ID: 23394