Christopher Shaw

      Professor Christopher Shaw

      Emeritus Professor

      Phone: +44 (0)28 9097 2129

      For media contact email comms.office@qub.ac.uk
      or call +44(0)2890 973091.

      Scopus Citations 5032

      1. 2018
      2. Published

        A Bowman-Birk type chymotrypsin inhibitor peptide from the amphibian, Hylarana erythraea

        Zhang, L., Chen, X., Wu, Y., Zhou, M., Ma, C., Xi, X., Chen, T., Walker, B., Shaw, C. & Wang, L. 11 Apr 2018 In : Scientific Reports. 8, 9 p., 5851. , 5851

        Research output: Research - peer-reviewArticle

      3. Published
      4. 2017
      5. Published

        Assessment of antimicrobial and wound healing effects of Brevinin-2Ta against the bacterium Klebsiella pneumoniae in dermally-wounded rats

        Liu, S., Long, Q., Xu, Y., Wang, J., Xu, Z., Wang, L., Zhou, M., Wu, Y., Chen, T. & Shaw, C. 30 Nov 2017 In : Oncotarget. 8, 67, p. 111369-111386

        Research output: Research - peer-reviewArticle

      6. Published
      7. Published
      8. Published
      9. Published
      10. Published

        Identification of a Novel Vasodilatory Octapeptide from the Skin Secretion of the African Hyperoliid Frog, Kassina senegalensis

        Du, Q., Wang, H., Ma, C., Wu, Y., Xi, X., Zhou, M., Chen, T., Shaw, C. & Wang, L. 19 Jul 2017 In : Molecules. 22, 9 p., 1215. , 1215

        Research output: Research - peer-reviewArticle

      11. Published

        Antidiabetic Micro-/Nanoaggregates from Ge-Gen-Qin-Lian-Tang Decoction Increase Absorption of Baicalin and Cellular Antioxidant Activity In Vitro

        Lin, D., Du, Q., Wang, H., Gao, G., Zhou, J., Ke, L., Chen, T., Shaw, C. & Rao, P. 17 Jul 2017 In : BioMed Research International. 2017, p. 1-8 9217912. , 9217912

        Research output: Research - peer-reviewArticle

      12. Published

        Ranatensin-HL: A Bombesin-Related Tridecapeptide from the Skin Secretion of the Broad-Folded Frog, Hylarana latouchii

        Lin, Y., Chen, T., Zhou, M., Wang, L., Su, S. & Shaw, C. 04 Jul 2017 In : Molecules. 22, 7, 1110. , 1110

        Research output: Research - peer-reviewArticle

      13. Published

        Novel Kazal-type Protease inhibitors from the skin secretion of the Splendid leaf frog, Cruziohyla calcarifer

        Proaño Bolaños, C., Li, R., Zhou, M., Wang, L., Xi, X., Tapia, E. E., Coloma, L. A., Chen, T. & Shaw, C. Jun 2017 In : EuPA Open Proteomics. 15, p. 1-13 13 p.

        Research output: Research - peer-reviewArticle

      14. Published
      15. Early online date
      16. Published
      17. Published

        A NOVEL PEPTIDE, QUB1999, IDENTIFIED IN PHYLLOMEDUSA BURMEISTERI SKIN

        Long, Q., Wu, Y., Wang, L., Chen, T. & Shaw, C. 2017 p. 104-104 1 p.

        Research output: Research - peer-reviewPoster

      18. 2016
      19. Published
      20. Published

        A Combined Molecular Cloning and Mass Spectrometric Method to Identify, Characterize, and Design Frenatin Peptides from the Skin Secretion of Litoria infrafrenata

        Wu, D., Gao, Y., Wang, L., Xi, X., Wu, Y., Zhou, M., Zhang, Y., Ma, C., Chen, T. & Shaw, C. 26 Oct 2016 In : Molecules. 21, 11, 12 p., 1429. , 1429

        Research output: Research - peer-reviewArticle

      21. Published
      22. Published
      23. Published
      24. Published
      25. Published

        Identification of Miscellaneous Peptides from the Skin Secretion of the European Edible Frog, Pelophylax kl. Esculentus

        Chen, X., Wang, H., Wang, L., Zhou, M., Chen, T. & Shaw, C. Aug 2016 In : The Protein Journal. 35, 4, p. 291-299 9 p.

        Research output: Research - peer-reviewArticle

      26. Published
      27. Published
      28. Published

        Baltikinin: A New Myotropic Tryptophyllin-3 Peptide Isolated from the Skin Secretion of the Purple-Sided Leaf Frog, Phyllomedusa baltea

        Shi, D., Xi, X., Wang, L., Gao, Y., Ma, C., Chen, H., Zhou, M., Chen, T. & Shaw, C. 08 Jul 2016 In : Toxins. 8, 7, 10 p., 213. , 213

        Research output: Research - peer-reviewArticle

      29. Published
      30. Published

        Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor

        Shi, D., Hou, X., Wang, L., Gao, Y., Wu, D., Xi, X., Zhou, M., Kwok , . H. F., Duan , J., Chen, T. & Shaw, C. 12 May 2016 In : Toxins. 8, 16 p., 144. , 144

        Research output: Research - peer-reviewArticle

      31. Published
      32. Published
      33. Published
      34. 2015
      35. Published
      36. Published

        Abnormal alterations in the Ca2+/CaV1.2/calmodulin/caMKII signaling pathway in a tremor rat model and in cultured hippocampal neurons exposed to Mg2+-free solution

        Lv, X., Guo, F., Xu, X., Chen, Z., Sun, X., Min, D., Cao, Y., Shi, X., Wang, L., Chen, T., Shaw, C., Gao, H., Hao, L. & Cai, J. Nov 2015 In : Molecular Medicine Reports. 12, 5, p. 6663-6671

        Research output: Research - peer-reviewArticle

      37. Published
      38. Published

        De novo sequencing of two novel peptides homologous to calcitonin-like peptides, from skin secretion of the Chinese Frog, Odorrana schmackeri

        Evaristo, G. P. C., Pinkse, M. W. H., Chen, T., Wang, L., Mohammed, S., Heck, A. J. R., Mathes, I., Lottspeich, F., Shaw, C., Albar, J. P. & Verhaert, P. D. E. M. Sep 2015 In : EuPA Open Proteomics. 8, p. 157-166 10 p.

        Research output: Research - peer-reviewArticle

      39. Published
      40. Published

        Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself

        McCrudden, C. M., O'Rourke, M. G., Cherry, K. E., Yuen, H-F., O'Rourke, D., Babur, M., Telfer, B. A., Thomas, H. D., Keane, P., Nambirajan, T., Hagan, C., O'Sullivan, J. M., Shaw, C., Williams, K. J., Curtin, N. J., Hirst, D. G. & Robson, T. 17 Feb 2015 In : PloS one. 10, 2, 16 p., e0118187. , e0118187

        Research output: Research - peer-reviewArticle

      41. Published
      42. Published
      43. Published
      44. 2014
      45. Published
      46. Published
      47. Published

        Ornithokinin (avian bradykinin) from the skin of the Chinese bamboo odorous frog, Odorrana versabilis

        Lyu, P., Ge, L., Wang, L., Guo, X., Zhang, H., Li, Y., Zhou, Y., Zhou, M., Chen, T. & Shaw, C. Aug 2014 In : Journal of peptide science. 20, 8, p. 618-624 7 p.

        Research output: Research - peer-reviewArticle

      48. Published

        Balteatide: A Novel Antimicrobial Decapeptide from the Skin Secretion of the Purple-Sided Leaf Frog, Phyllomedusa baltea

        Ge, L., Chen, X., Ma, C., Zhou, M., Xi, X., Wang, L., Ding, A., Duan, J., Chen, T. & Shaw, C. 26 Jun 2014 In : The Scientific World Journal. 2014, 8 p., 176214. , 176214

        Research output: Research - peer-reviewArticle

      49. Published
      50. Published
      51. Published

        Hylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii

        Lin, Y., Hu, N., Lyu, P., Ma, J., Wang, L., Zhou, M., Guo, S., Chen, T. & Shaw, C. Apr 2014 In : Amino Acids. 46, 4, p. 901-909 9 p.

        Research output: Research - peer-reviewArticle

      52. Published

        Bradykinin-related peptides (BRPs) from skin secretions of three genera of phyllomedusine leaf frogs and their comparative pharmacological effects on mammalian smooth muscles

        Jiang, Y., Xi, X., Ge, L., Yang, N., Hou, X., Ma, J., Ma, C., Wu, Y., Guo, X., Li, R., Zhou, M., Wang, L., Chen, T. & Shaw, C. Feb 2014 In : Peptides. 52, p. 122-133 12 p.

        Research output: Research - peer-reviewArticle

      53. Published

        AcT-2: A Novel Myotropic and Antimicrobial Type 2 Tryptophyllin from the Skin Secretion of the Central American Red-Eyed Leaf Frog, Agalychnis callidryas

        Ge, L., Lyu, P., Zhou, M., Zhang, H., Wan, Y., Li, B., Li, R., Wang, L., Chen, T. & Shaw, C. 2014 In : The Scientific World Journal. 2014, 7 p., 158546. , 158546

        Research output: Research - peer-reviewArticle

      54. Published

        Feleucins: Novel Bombinin Precursor-Encoded Nonapeptide Amides from the Skin Secretion of Bombina variegata

        Bai, B., Hou, X., Wang, L., Ge, L., Luo, Y., Ma, C., Zhou, M., Duan, J., Chen, T. & Shaw, C. 2014 In : BioMed Research International. 2014, 8 p., 671362. , 671362

        Research output: Research - peer-reviewArticle

      55. 2013
      56. Published

        Ranachensinin: A Novel Aliphatic Tachykinin from the Skin Secretion of the Chinese Brown Frog, Rana chensinensis

        Wu, Y., Li, R., Ma, J., Zhou, M., Wang, L., McClure, T. I., Cai, J., Chen, T. & Shaw, C. Nov 2013 In : Protein and Peptide Letters. 20, 11, p. 1217-1224

        Research output: Research - peer-reviewArticle

      57. Published
      58. Published
      59. Published
      60. Published
      61. Published

        Medusins: a new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs

        Xi, X., Li, R., Jiang, Y., Lin, Y., Wu, Y., Zhou, M., Xu, J., Wang, L., Chen, T. & Shaw, C. Jun 2013 In : Biochimie. 95, 6, p. 1288-1296

        Research output: Research - peer-reviewArticle

      62. Published

        Parallel Peptidome and Transcriptome Analyses of Amphibian Skin Secretions Using Archived Frozen Acid-Solvated Samples

        Bai, B., Zhang, Y., Wang, H., Zhou, M., Yu, Y., Ding, S., Chen, T., Wang, L. & Shaw, C. Jun 2013 In : Molecular biotechnology. 54, 2, p. 187-197

        Research output: Research - peer-reviewArticle

      63. Published

        Purification, characterization and molecular cloning of chymotrypsin inhibitor peptides from the venom of Burmese Daboia russelii siamensis

        Guo, C-T., McClean, S., Shaw, C., Bjourson, A. J., Rao, P-F. & Ye, M-Y. 01 May 2013 In : Peptides. 43, p. 126-132 7 p.

        Research output: Research - peer-reviewArticle

      64. Published

        Senegalin: a novel antimicrobial/myotropic hexadecapeptide from the skin secretion of the African running frog, Kassina senegalensis

        Wang, H., Li, R., Xi, X., Meng, T., Zhou, M., Wang, L., Zhang, Y., Chen, T. & Shaw, C. May 2013 In : Amino Acids. 44, 5, p. 1347-1355

        Research output: Research - peer-reviewArticle

      65. Published

        The alterations of Ca2+/Calmodulin/CaMKII/CaV1.2 signaling in experimental models of Alzheimer's disease and vascular dementia

        Min, D., Guo, F., Zhu, S., Xu, X., Mao, X., Cao, Y., Lv, X., Gao, Q., Wang, L., Chen, T., Shaw, C., Hao, L. & Cai, J. 22 Mar 2013 In : Neuroscience Letters. 538, p. 60-65 6 p.

        Research output: Research - peer-reviewArticle

      66. Published

        Vasorelaxin: A Novel Arterial Smooth Muscle-Relaxing Eicosapeptide from the Skin Secretion of the Chinese Piebald Odorous Frog (Odorrana schmackeri)

        Wu, Y., Wang, L., Lin, C., Lin, Y., Zhou, M., Chen, L., Connolly, B., Zhang, Y., Chen, T. & Shaw, C. 06 Feb 2013 In : PLoS One. 8, 2, e55739. , e55739

        Research output: Research - peer-reviewArticle

      67. Published

        The chains of the heterodimeric amphibian skin antimicrobial peptide, distinctin, are encoded by separate messenger RNAs

        Evaristo, G., Pinkse, M., Wang, L., Zhou, M., Wu, Y., Wang, H., Chen, T., Shaw, C. & Verhaert, P. 14 Jan 2013 In : Journal of Proteomics. 78, p. 245-253 9 p.

        Research output: Research - peer-reviewArticle

      68. Published
      69. Published

        The up-regulation of voltage-gated sodium channels subtypes coincides with an increased sodium current in hippocampal neuronal culture model

        Guo, F., Xu, X., Cai, J., Hu, H., Sun, W., He, G., Shao, D., Wang, L., Chen, T., Shaw, C., Zhu, T. & Hao, L. 2013 In : Neurochemistry International. 62, 3, p. 287-295 9 p.

        Research output: Research - peer-reviewArticle

      70. 2012
      71. Published

        Cloning of cDNAs and molecular characterisation of C-type lectin-like proteins from snake venoms

        Feng, J., Chen, T., Zhou, M. & Shaw, C. 15 Dec 2012 In : Toxicon. 60, 8, p. 1363–1369 7 p.

        Research output: Research - peer-reviewArticle

      72. Published
      73. Published

        PD-sauvagine: a novel sauvagine/corticotropin releasing factor analogue from the skin secretion of the Mexican giant leaf frog, Pachymedusa dacnicolor

        Zhou, Y., Jiang, Y., Wang, R., Bai, B., Zhou, M., Chen, T., Cai, J., Wang, L. & Shaw, C. Sep 2012 In : Amino Acids. 43, 3, p. 1147-1156 10 p.

        Research output: Research - peer-reviewArticle

      74. Published
      75. Published

        A novel Kazal-type trypsin inhibitor from the skin secretion of the Central American red-eyed leaf frog, Agalychnis callidryas.

        Li, R., Wang, H., Jiang, Y., Yu, Y., Wang, L., Zhou, M., Zhang, Y., Chen, T. & Shaw, C. Jun 2012 In : Biochimie. 94, 6, p. 1376-1381 6 p.

        Research output: Research - peer-reviewArticle

      76. Published
      77. Published

        Helokinestatin-7 peptides from the venoms of Heloderma lizards

        Ma, C., Wang, H., Wu, Y., Zhou, M., Lowe, G., Wang, L., Zhang, Y., Chen, T. & Shaw, C. Jun 2012 In : Peptides. 35, 2, p. 300-305 6 p.

        Research output: Research - peer-reviewArticle

      78. Published

        Functional peptidomics of amphibian skin secretion: A novel Kunitz-type chymotrypsin inhibitor from the African hyperoliid frog, Kassina senegalensis

        Wang, H., Wang, L., Zhou, M., Yang, M., Ma, C., Chen, T., Zhang, Y., Zeller, M., Hornshaw, M. & Shaw, C. Mar 2012 In : Biochimie. 94, 3, p. 891-899 9 p.

        Research output: Research - peer-reviewArticle

      79. Published

        Donepezil attenuates hippocampal neuronal damage and cognitive deficits after global cerebral ischemia in gerbils.

        Min, D., Mao, X., Wu, K., Cao, Y., Guo, F., Zhu, S., Xie, N., Wang, L., Chen, T., Shaw, C. & Cai, J. 21 Feb 2012 In : Neuroscience Letters. 510, 1, p. 29-33 5 p.

        Research output: Research - peer-reviewArticle

      80. 2011
      81. Published

        Kasstasin: A novel potent vasoconstrictor peptide from the skin secretion of the African red-legged running frog, Kassina maculata

        Li, X. H., Feng, W., Zhou, M., Ma, C., Chen, T., Zeller, M., Hornshaw, M., Wang, L. & Shaw, C. Sep 2011 In : Biochimie. 93, 9, p. 1537-1542 6 p.

        Research output: Research - peer-reviewArticle

      82. Published

        Limnonectins: A new class of antimicrobial peptides from the skin secretion of the Fujian large-headed frog (Limnonectes fujianensis)

        Wu, Y., Zhou, M., Wang, L., Ma, C., Chen, X., Bai, B., Chen, T. & Shaw, C. Jun 2011 In : Biochimie. 93, 6, p. 981-987 7 p.

        Research output: Research - peer-reviewArticle

      83. Published
      84. Published
      85. Published
      86. Published

        Kassorins: Novel innate immune system peptides from skin secretions of the African hyperoliid frogs, Kassina maculata and Kassina senegalensis

        Chen, H., Wang, L., Zeller, M., Hornshaw, M., Wu, Y., Zhou, M., Li, J., Hang, X., Cai, J., Chen, T. & Shaw, C. Jan 2011 In : Molecular Immunology. 48, 4, p. 442-451 10 p.

        Research output: Research - peer-reviewArticle

      87. Published

        RP-LC with fluorescence detection of amino acids in rat brain synaptosomes

        Mao, X., Cao, Y., Min, D., Min, D., Xie, N., Chen, T., Shaw, C. & Cai, J. Jan 2011 In : Chromatographia. 73, 1-2, p. 157-163 7 p.

        Research output: Research - peer-reviewArticle

      88. 2010
      89. Published

        Up-regulation of GABA transporters and GABAA Receptor α1 subunit in tremor rat hippocampus

        Mao, X., Guo, F., Yu, J., Min, D., Wang, Z., Xie, N., Chen, T., Shaw, C. & Cai, J. 17 Dec 2010 In : Neuroscience Letters. 486, 3, p. 150-155 16 p.

        Research output: Research - peer-reviewArticle

      90. Published

        Functional and Structural Diversification of the Anguimorpha Lizard Venom System

        Fry, B. G. , Winter, K. , Norman, J. A. , Roelants, K. , Nabuurs, R. J. A. , van Osch, M. J. P. , Teeuwisse, W. M. , van der Weerd, L. , Mcnaughtan, J. E. , Kwok, H. F. , Scheib, H. , Greisman, L. , Kochva, E. , Miller, L. J. , Gao, F. , Karas, J. , Scanlon, D. , Lin, F. , Kuruppu, S. , Shaw, C. & 2 others Wong, L. & Hodgson, W. C. 01 Nov 2010 In : Molecular and Cellular Proteomics. 9, 11, p. 2369-2390 22 p.

        Research output: Research - peer-reviewArticle

      91. Published
      92. Published
      93. Published
      94. Published
      95. Published
      96. Published
      97. Published
      98. Published
      99. Published
      100. Published
      101. Published
      102. Published
      103. Published
      104. Published
      105. Published

        Phylloseptin-1 (PSN-1) from Phyllomedusa sauvagei skin secretion: a novel broad-spectrum antimicrobial peptide with antibiofilm activity

        Zhang, R., Zhou, M., Wang, L., McGrath, S., Chen, T., Chen, X. & Shaw, C. Jul 2010 In : Molecular Immunology. 47, 11-12, p. 2030-2037 8 p.

        Research output: Research - peer-reviewArticle

      106. Published

        Antimicrobial activity of short, synthetic cationic lipopeptides.

        McLaughlin, M., Shaw, C., Gorman, S., Gilmore, B. & Laverty, G. Jun 2010 In : Chemical Biology & Drug Design. 75(6), 6, p. 563-569 7 p.

        Research output: Research - peer-reviewArticle

      107. Published

        Peptide DV-28 amide: An inhibitor of bradykinin-induced arterial smooth muscle relaxation encoded by Bombina orientalis skin kininogen-2

        Wang, L., Chen, Y., Zhou, M., Yang, M., Chen, T., Sui, D. Y. & Shaw, C. May 2010 In : Peptides. 31, 5, p. 979-982 4 p.

        Research output: Research - peer-reviewArticle

      108. Published

        Nigrocin-2 peptides from Chinese Odorrana frogs – integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis

        Wang, L., Evaristo, G., Zhou, M., Pinkse, M., Wang, M., Xu, Y., Jiang, X., Chen, T., Rao, P., Verhaert, P. & Shaw, C. Mar 2010 In : The FEBS Journal. 277, 6, p. 1519-1531 13 p.

        Research output: Research - peer-reviewArticle

      109. Published

        Novel Venom Proteins Produced by Differential Domain-Expression Strategies in Beaded Lizards and Gila Monsters (genus Heloderma)

        Fry, B. G., Roelants, K., Winter, K., Hodgson, W. C., Griesman, L., Kwok, H. F., Scanlon, D., Karas, J., Shaw, C., Wong, L. & Norman, J. A. Feb 2010 In : Molecular Biology and Evolution. 27, 2, p. 395-407 13 p.

        Research output: Research - peer-reviewArticle

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