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    Research Statement

    My research theme focuses on the interplay between the innate immune response to infection, and the reparative and regenerative potential of adult stem cells. I am particularly interested in the potential for the adult stem cell secretome to modulate the local microenvironment. I am also interested in the role of neuro-inflammatory / innate immune peptides in adult stem cell differentiation. My work on pain and neurogenic inflammation, and the neuro-inflammatory response to infection, has naturally extended into the related field of transient receptor potential (TRP) channel research and the modulation of these important channels during the inflammatory and regenerative processes. I also have an interest in studying the stability of host defence peptides and proteins in the inflammatory milieu, and in the design of peptide mimetics with resistance to proteinases and enhanced efficacy against bacterial and fungal pathogens in biofilm form. I have published >60 peer reviewed articles in learned journals and have been successful in obtaining competitive research grant income from a range of funding agencies such as EU INTERREG, NC3Rs, MRC, Pain Relief Foundation, Animal Free Research, HSC R&D Office and the British Society for Antimicrobial Chemotherapy. I currently chair the successful regenerative medicine (REMERGE) group,  a multidisciplinary team of academic and clinical researchers, with a focus on using regenerative medicine techniques to study and treat a range of clinical conditions.

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    Frequent Journals

    • Journal of Dental Research

      ISSNs: 0022-0345

      Additional searchable ISSN (Electronic): 1544-0591

      AMER ASSOC DENTAL RESEARCH

      Scopus rating (2018): SJR 2.14 SNIP 2.232

      Journal

    • Journal of Clinical Periodontology

      ISSNs: 0303-6979

      Additional searchable ISSN (Electronic): 1600-051X

      Blackwell Munksgaard

      Scopus rating (2018): SJR 2.581 SNIP 2.088

      Journal

    • Irish journal of medical science

      ISSNs: 0021-1265

      Additional searchable ISSN (Electronic): 1863-4362

      Springer-Verlag London Ltd

      Scopus rating (2018): SJR 0.371 SNIP 0.499

      Journal

    • Archives of Oral Biology

      ISSNs: 0003-9969

      Elsevier Limited

      Scopus rating (2018): SJR 0.61 SNIP 0.843

      Journal

    • Journal of Endodontics

      ISSNs: 0099-2399

      Additional searchable ISSN (Electronic): 1878-3554

      Elsevier Inc.

      Scopus rating (2018): SJR 1.822 SNIP 1.546

      Journal

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    Contribution to conference papers, events and activities

    ID: 17278