Phone: +44 (0)28 9097 6474

    For media contact email comms.office@qub.ac.uk
    or call +44(0)2890 973091.

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    Research Interests

    Epigenetic Regulation of Differentiation and Disease

    We are particularly interested in studying how cell-fates are specified during development and miss-specified in diseases.

    The research in my lab is aimed at achieving an integrated molecular and systems-level understanding of the mechanisms by which epigenetic machinery and transcription factors contribute to transcriptional reprogramming that defines cell-type identity during development and how this communication is altered in diseases such as cancer. To investigate these questions, we employ a multidisciplinary approach combining cutting-edge epigenetics and genomics together with computational biology tools in sophisticated and defined models of cellular differentiation and carcinogenesis.

    The key topics of research is my lab are:

    • Transcription Factors and Cell-Fate Specification
    • Epigenomics of Cell-type Identity
    • Signaling to Chromatin Crosstalk
    • Epigenetic Regulation of Neurogenesis
    • Chromatin and Cancer
    • Systems Biology of Gene Regulatory Networks

     Please visit the lab web page for details.

     

    Willingness to take PhD students

    Yes

    Frequent Journals

    • The EMBO Journal

      ISSNs: 0261-4189, 1469-221X

      Additional searchable ISSN (Electronic): 1460-2075

      NATURE PUBLISHING GROUP

      Scopus rating (2018): CiteScore 8.28 SJR 4.459 SNIP 1.282

      Journal

    • Genome Research

      ISSNs: 1088-9051

      Additional searchable ISSN (Electronic): 1088-9051

      Cold Spring Harbor Laboratory Press

      Scopus rating (2018): CiteScore 10.07 SJR 10.205 SNIP 2.462

      Journal

    • PLoS Genetics

      ISSNs: 1553-7390, 1553-7404

      Additional searchable ISSN (Electronic): 1553-7404

      Public Library of Science

      Scopus rating (2018): CiteScore 5 SJR 4.001 SNIP 1.286

      Journal

    • Nature Communications

      ISSNs: 2041-1723

      Nature Publishing Group

      Scopus rating (2018): CiteScore 12.19 SJR 5.992 SNIP 2.805

      Journal

    • Nature Genetics

      ISSNs: 1061-4036

      Additional searchable ISSN (Electronic): 1546-1718

      Nature Publishing Group

      Scopus rating (2018): SJR 21.508 SNIP 5.477

      Journal

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