Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

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    Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.


    Original languageEnglish
    Number of pages6
    Pages (from-to)492-497
    JournalGreen Chemistry
    Journal publication date2009
    Issue number4
    Early online date18 Feb 2009
    Publication statusPublished - 2009

    ID: 702980