Bioactive Compounds from Marine Organisms: Potential for Bone Growth and Healing

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    Marine organisms represent a highly diverse reserve of bioactives which could aid in the treatment of a wide range of diseases, including various musculoskeletal conditions. Osteoporosis in particular would benefit from a novel and effective marine-based treatment, due to its large disease burden and the inefficiencies of current treatment options. Osteogenic bioactives have been isolated from many marine organisms, including nacre powder derived from molluscan shells and fucoidan—the sulphated polysaccharide commonly sourced from brown macroalgae. Such extracts and compounds are known to have a range of osteogenic effects, including stimulation of osteoblast activity and mineralisation, as well as suppression of osteoclast resorption. This review describes currently known soluble osteogenic extracts and compounds from marine invertebrates and algae, and assesses their preclinical potential

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    • Bioactive Compounds from Marine Organisms: Potential for Bone Growth and Healing

      Rights statement: Copyright 2018 the authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.

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    DOI

    Original languageEnglish
    Article number340
    Number of pages16
    JournalMarine Drugs
    Journal publication date18 Sep 2018
    Issue number9
    Volume16
    DOIs
    Publication statusPublished - 18 Sep 2018

    ID: 163259405