Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei

      Research output: Research - peer-reviewArticle

      Early online date
      • Michelle E Wood
      • Rebecca E Stockwell
      • Graham R Johnson
      • Kay A Ramsay
      • Laura J Sherrard
      • Timothy J Kidd
      • Joyce Cheney
      • Emma L Ballard
      • Peter O'Rourke
      • Nassib Jabbour
      • Claire E Wainwright
      • Luke D Knibbs
      • Peter D Sly
      • Lidia Morawska
      • Scott C Bell

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      The airborne route is a potential pathway in the person-to-person transmission of bacterial strains among cystic fibrosis (CF) populations. In this cross-sectional study, we investigate the physical properties and survival of common non-Pseudomonas aeruginosa CF pathogens generated during coughing. We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min. These results suggest that airborne person-to-person transmission is plausible for the CF pathogens we measured.

      Documents

      • Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei

        Rights statement: © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.This work is made available online in accordance with the publisher’s policies. Please refer to any applicable terms of use of the publisher.

        Accepted author manuscript, 242 KB, PDF-document

      DOI

      Original languageEnglish
      JournalThorax
      Journal publication date07 Apr 2018
      Early online date07 Apr 2018
      DOIs
      StateEarly online date - 07 Apr 2018

        Research areas

      • Journal Article

      ID: 149080788