Factors affecting recruitment and attrition in randomised controlled trials of complementary and alternative medicine for pregnancy-related Issues
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Background: Pregnant women frequently
experience aches and pains. However, they
are limited in the analgesics they can use, with
many turning to Complementary and Alternative
Medicine (CAM) for relief. However, trials
investigating CAM for pregnancy-related issues
encounter issues with recruitment and attrition.
Aim: To explore factors related to recruitment
and attrition in pregnancy CAM trials.
Methods: Data was gathered from an antenatal
CAM trial. During foetal anomaly appointments,
women meeting inclusion criteria
were invited to participate in a trial exploring
the CAM for pregnancy back and pelvic pain.
Numbers of women invited and eligible were
recorded. Reasons for noninterest were noted
and analysed. Focus groups exploring trial experience
of participants were also conducted.
Results: Of the 428 women invited to participate,
376 were eligible and just under a
quarter participated. Reasons for non-participation
included concerns about CAM and lack
of interest in participation in research. Other
factors negatively affecting recruitment included
recruitment timing, competition for participants, limited support from staff, and inadequate
trial promotion. Factors encouraging recruitment
included being interested in research and
seeking pain relief. Reasons for dropping out
were time constraints, travel issues, work commitments,
and pregnancy issues. Several women
in the sham and usual care group dropped out
due to dissatisfaction with treatment allocation.
Discussion: Recruitment in this CAM trial
mirror those on non-CAM trials in pregnancy,
highlighting the challenges of engaging pregnant
women in research. Consideration needs to be
given to strategies to reduce the burden of study
participation during pregnancy. Women were
not always informed about the study. This is
common in trials due to understaffing. The key
issue for attrition was the sham treatment was
unacceptable to many women.
Conclusion: CAM researchers must explore
problems encountered with recruitment and
attrition so that evidence-based implementation
strategies to address the issues can be developed.
|Title of host publication||Factors affecting recruitment and attrition in randomised controlled trials of complementary and alternative medicine for pregnancy-related Issues|
|Number of pages||47|
|State||Published - 17 Apr 2018|
|Event||RCN annual research Conference 2018 - Birmingham, United Kingdom|
Duration: 16 Apr 2018 → 18 Apr 2018
|Conference||RCN annual research Conference 2018|
|Period||16/04/2018 → 18/04/2018|